HFNC Versus Conventional Nasal Cannula During EBUS Procedure: a Randomised Controlled Trial

Status: Recruiting
Location: See all (4) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

EBUS bronchoscopy is performed in most centers under local anesthesia and moderate sedation. Both the bronchoscopy itself and the sedation can lead to decreased ventilation and a drop in oxygen saturation in the body. Typically, oxygen is administered during the procedure via a nasal cannula at a flow rate of 6l/min. The aim of the study is to compare a new method - a nasal cannula with high flow - to the standard cannula. The primary objective is to demonstrate that the new method is more effective at preventing desaturation during the procedure. Patients will be randomized into two groups before bronchoscopy and monitored. The bronchoscopy will be performed in the same way for both groups. The only difference between the groups will be in the method of oxygen administration during EBUS bronchoscopy.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Adult patients older than 18 years, ASA I - III, with normal pre-procedural pO2 (\> 8.0 kPa) and pCO2 (\< 6.7 kPa) levels without oxygen supplementation

Locations
Other Locations
Croatia
University Hospital Centre Zagreb - Jordanovac
RECRUITING
Zagreb
Greece
National and Kapodistrian University of Athens
RECRUITING
Athens
Portugal
Clinica Universitaria de Pneumologia, Hospital de Santa Maria
RECRUITING
Lisbon
Slovenia
University Clinic Golnik
RECRUITING
Golnik
Contact Information
Primary
Ales Rozman, MD, PhD
ales.rozman@klinika-golnik.si
+38641313811
Backup
Sonja Badovinac, MD, PhD
sonjabadovinac1@gmail.com
+385916302152
Time Frame
Start Date: 2024-03-01
Estimated Completion Date: 2024-11-01
Participants
Target number of participants: 150
Treatments
Active_comparator: Standard nasal cannula 6l/min, 100% O2
Standard procedure during EBUS bronchoscopy
Experimental: High - flow nasal cannula 60l/min, 45% O2
The new method
Related Therapeutic Areas
Sponsors
Collaborators: National and Kapodistrian University of Athens, Universidade Nova de Lisboa, Clinical Hospital Centre Zagreb
Leads: The University Clinic of Pulmonary and Allergic Diseases Golnik

This content was sourced from clinicaltrials.gov