Assessment of the Safety and Performance of the AB1 Electrosurgical System for Bronchoscopic Microwave Ablation of Lung Tissue in Surgical Candidates

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Observational
SUMMARY

The overall purpose of this study is to characterise the clinical safety and performance of the Creo Medical MicroBlate™ Flex AB1 instrument in patients with pathologically confirmed malignancy eligible for surgical resection of their nodule, receiving bronchoscopic ablation prior to surgery.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
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∙ Patients who:

• Have signed informed consent.

• Subject is willing and able to comply with all aspects of the treatment and evaluation schedule.

• Are ≥ 18 years old.

• Have lung lesion(s)/nodule(s) which are histopathological-confirmed as cancer.

• Have soft tissue lung lesion(s):

‣ ≤ 30 mm in the largest dimension of the pulmonary window for Stage A.

⁃ ≤ 20 mm in the largest dimension of the pulmonary window for Stage B.

• Are candidates for surgical resection as determined by a multi-disciplinary team (MDT) or tumour board.

• Greater than 10 mm of tumour-free lung parenchyma between target tumour and pleura or fissure.

• Subject is willing and able to comply with the study protocol requirements.

• Are assigned an ASA (American Society of Anaesthesiologists) score of ≤ 3 or the patient is deemed fit for general anaesthesia.

Locations
Other Locations
Netherlands
Amsterdam University Medical Centres, Location AMC, Meibergdreef 9
RECRUITING
Amsterdam
Contact Information
Primary
Charlie Campion
Charlie.Campion@creomedical.com
+44 7939 600137
Backup
Annie Goulding
Annie.Goulding@creomedical.com
+44 1291 606 005
Time Frame
Start Date: 2025-06-17
Estimated Completion Date: 2026-06
Participants
Target number of participants: 30
Treatments
Microwave ablation
Patients with a malignant lung nodule who are candidates for surgical resection.
Related Therapeutic Areas
Sponsors
Leads: Creo Medical Limited

This content was sourced from clinicaltrials.gov