Endoscopy Clinical Trials

Clinical trials related to Endoscopy Procedure

Protective Benefits of a Clear Liquid Diet on Residual Gastric Content in Patients Taking Glucagon Like Peptide-1 Receptor Agonist Prior to Anesthesia

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this study is to determine if prolonged fasting from solids and transitioning to a CLD for 24 hours is protective to decrease RGC in patients on GLP-1 RAs presenting for upper endoscopy, to determine if prolonged fasting is associated with increased thirst, hunger and anxiety, To determine if signs and symptoms of nausea, vomiting, retching, abdominal bloating, and abdominal pain are present on the day of surgery, to see if there is any variability between preoperative gastric ultrasound assessment and volume of gastric contents visualized on upper endoscopy, to determine time of gastric emptying by serial Gastric ultrasonography (GUS) scans every 2 hours in subjects who presented with an initial at-risk scan, to determine the choice of anesthesia used based on preoperative GUS results, to determine if there were any adverse events recorded in this study group, to determine if duration of GLP-1 RA therapy has an association with residual gastric content (RGC). and to determine if dosing of GLP-1 RA has an association with RGC.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients taking Glucagon Like Peptide-1 Receptor (GLP-1 RA) agonists

• Undergoing upper endoscopy only - no colonoscopy due to prep

Locations
United States
Texas
The University of Texas Health Science Center at Houston
RECRUITING
Houston
Contact Information
Primary
Sudipta Sen, MD, FASA
Sudipta.Sen@uth.tmc.edu
(713) 500-6202
Backup
Paul Potnuru
Paul.Potnuru@uth.tmc.edu
(713) 500-6271
Time Frame
Start Date: 2025-10-30
Estimated Completion Date: 2026-05-01
Participants
Target number of participants: 136
Treatments
Experimental: GLP-1 RA users with prolonged fasting instructions
Active_comparator: GLP-1 RA users with standard NPO instructions
Related Therapeutic Areas
Sponsors
Leads: The University of Texas Health Science Center, Houston

This content was sourced from clinicaltrials.gov