Perioperative Dynamics of Energy Expenditure in Lewis-Santy Oesophagectomy Patients

Status: Recruiting
Location: See all (4) locations...
Study Type: Observational
SUMMARY

Carcinological oesophageal resection surgery is one of the so-called major digestive surgeries, i.e. involving a high perioperative risk (morbidity and mortality) in patients who are malnourished or at high risk of malnutrition. Nutritional therapy for these patients is an important part of overall perioperative management. Lewis-Santy oesophageal surgery requires a thoracic approach (thoracotomy or thoracoscopy) and an abdominal approach (laparotomy or laparoscopy). Resumption of oral feeding is contraindicated in the immediate postoperative period. The use of a feeding jejunostomy is not systematic. The methods used to manage artificial nutritional support vary between centres, but the foreseeable duration of fasting and/or intake of less than 50% of nutritional requirements is always greater than 5 days. At present, total energy requirements are calculated using formulae that take into account the patient's inflammatory state (stable, unstable or stabilised patient), theoretical ideal weight and previous nutritional status, in order to come as close as possible to actual energy expenditure, and are the subject of perioperative nutrition protocols specific to each centre. Indirect calorimetry makes it possible to reliably measure energy expenditure during the perioperative period. The OESOCAL study continues this line of reasoning. It assumes that energy expenditure may vary according to the surgical approach, and that indirect calorimetry can be used to optimise nutritional support in order to avoid over- or under-nutrition, which may be responsible for an increase in infectious complications.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Any adult patient admitted for scheduled digestive surgery for Lewis Santy oesophagectomy whose care pathway includes a stay in an intensive care unit or continuing care unit.

• Member or beneficiary of a social protection scheme

• Patient who has read and understood the information letter and does not object to taking part in the study.

Locations
Other Locations
France
Service d'Anesthésie-Réanimation
NOT_YET_RECRUITING
Amiens
Department of Anaesthesia and Intensive Care
NOT_YET_RECRUITING
Brest
Surgical Intensive Care Department
RECRUITING
Rouen
Department of Anaesthesia, Intensive Care and Perioperative Medicine
NOT_YET_RECRUITING
Vandœuvre-lès-nancy
Contact Information
Primary
David DM MALLET, Director
Secretariat.DRC@chu-rouen.fr
2 32 88 82 65
Backup
Vincent VF FERRANTI, Arc
vincent.ferranti@chu-rouen.fr
2 32 88 82 65
Time Frame
Start Date: 2024-09-01
Estimated Completion Date: 2028-01-02
Participants
Target number of participants: 120
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Rouen

This content was sourced from clinicaltrials.gov