FIT Versus Colonoscopy for Post-polypectomy Surveillance
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
From observational studies, it is know that the risk of developing colorectal cancer after polyp removal is lower if the patients adheres to surveillance recommendations. However, colonoscopy is burdensome for patients and colonoscopy availability is limited in many parts of the world. In addition, more than half of surveillance colonoscopies are without any findings. The trial investigates whether surveillance using fecal testing for blod is as good as colonoscopy after removal of colorectal polyps.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 75
Healthy Volunteers: f
View:
• High-quality baseline colonoscopy with adequat cleansing and cecal intubation
• Remocval of at least one advanced adenoma
• Clean colon (all polyps removed)
• Signed informed consent
Locations
Other Locations
Norway
Sørlandet sykehus HF
RECRUITING
Arendal
Contact Information
Primary
Øyvind Holme
oyvind.holme@sshf.no
004738073000
Backup
Michael Bretthauer
michael.bretthauer@medisin.uio.no
004790132480
Time Frame
Start Date: 2026-01-09
Estimated Completion Date: 2050-01-01
Participants
Target number of participants: 4000
Treatments
Active_comparator: Colonoscopy
Colonoscopy surveillance after polyp removal
Experimental: Fecal blood testing
Fecal testing as surveillance after polypectomy
Related Therapeutic Areas
Sponsors
Collaborators: Viborg Regional Hospital, Vestre Viken Hospital Trust, Sykehuset Telemark Hospital Trust, Sykehuset i Vestfold HF, Randers Regional Hospital, Helsinki University Central Hospital, Helse Stavanger HF, Helse Møre og Romsdal HF, St. Olavs Hospital, Gødstrup Hospital, University Hospital of Northern Norway, Tromsø, Norway, University Hospital, Akershus, Turku University Hospital, Horsens Hospital, Sykehuset Ostfold
Leads: Sorlandet Hospital HF