Endoscopy Clinical Trials

Clinical trials related to Endoscopy Procedure

Evaluation of The Effect of Holy Basil in The Treatment of Patients With Dyspepsia

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2/Phase 3
SUMMARY

The goal of this clinical trial is to evaluate whether holy basil extract can reduce gastric inflammation and improve symptoms in adult patients with dyspepsia. The main questions it aims to answer are: * Does holy basil extract reduce gastric mucosal inflammation as measured by histopathology? * Does holy basil extract improve dyspeptic symptoms, endoscopic findings, gastric pH, duodenal eosinophil counts, and systemic inflammation (serum IL-6)? Participants will: * Take 300 mg of holy basil extract orally once daily for 28 days * Complete symptom questionnaires and diaries during treatment * Undergo upper endoscopy with biopsy and intragastric pH monitoring before and after treatment * Provide blood samples for inflammatory marker measurement * Be monitored for safety and adverse events

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Participants aged 18 years and older.

• Presence of dyspeptic symptoms, assessed by the Leeds Dyspepsia Questionnaire with a score of at least 5 or higher.

Locations
Other Locations
Thailand
Faculty of Medicine Siriraj Hospital, Mahidol University
RECRUITING
Bangkok Noi
Contact Information
Primary
Monthira Maneerattanaporn, MD
monthira.man@mahidol.ac.th
+66 24197281
Backup
Pubet Weeranawin, MD
Pubet.w@gmail.com
+66 24197281
Time Frame
Start Date: 2026-02-13
Estimated Completion Date: 2026-12
Participants
Target number of participants: 27
Treatments
Experimental: Holy basil
All participants will receive holy basil extract 300 mg orally once daily for 28 days.
Related Therapeutic Areas
Sponsors
Leads: Mahidol University

This content was sourced from clinicaltrials.gov