Ultrasound-Guided External Oblique Intercostal Block Versus Erector Spinae Plane Block for Postoperative Analgesia After Laparoscopic Cholecystectomy: A Randomized Controlled Study

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This randomized controlled study aims to compare the effects of the external oblique intercostal block (EOIB) and the erector spinae plane block (ESPB) on postoperative analgesia in adult patients undergoing elective laparoscopic cholecystectomy. Both EOIB and ESPB are ultrasound-guided regional anesthesia techniques currently used in clinical practice to improve postoperative pain control as part of multimodal analgesia strategies. Laparoscopic cholecystectomy is a common minimally invasive surgical procedure; however, patients may still experience postoperative pain that can increase opioid consumption and delay recovery. Identifying the most effective regional anesthesia technique may improve postoperative analgesia and patient recovery. In this study, eligible patients will be randomly assigned to receive either bilateral EOIB or bilateral ESPB in addition to standardized general anesthesia and postoperative patient-controlled analgesia. Postoperative pain scores, opioid consumption, quality of recovery, postoperative nausea and vomiting, and block-related complications will be evaluated during the first 24 hours after surgery. The study aims to provide comparative clinical evidence regarding the analgesic effectiveness of these two regional anesthesia techniques.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Age between 18 and 80 years

• Scheduled to undergo elective laparoscopic cholecystectomy

• Classified as American Society of Anesthesiologists (ASA) physical status I-III

• Ability to understand and operate a patient-controlled analgesia (PCA) device

• Provision of written informed consent

Locations
Other Locations
Turkey
Karabuk Training and Research Hospital, Department of Anesthesiology and Reanimation
RECRUITING
Karabük
Department of Anesthesiology and Reanimation, Samsun City Hospital
RECRUITING
Samsun
Contact Information
Primary
Elif Sarikaya Ozel, M.D.
elsarikay2@gmail.com
+905462361453
Time Frame
Start Date: 2026-01-01
Estimated Completion Date: 2026-04-15
Participants
Target number of participants: 60
Treatments
Active_comparator: Group EOIB
Patients allocated to the EOIB group will be transferred to the regional anesthesia area and monitored approximately 45 minutes before surgery. With the patient in the supine position, bilateral ultrasound-guided external oblique intercostal block (EOIB) will be performed. A total volume of 60 mL of 0.25% bupivacaine (30 mL per side) will be injected. General anesthesia will then be administered according to standard practice. In the postoperative period, additional analgesia will be provided using intravenous morphine patient-controlled analgesia (PCA).
Active_comparator: Group ESPB
Patients allocated to the ESPB group will be transferred to the regional anesthesia area and monitored approximately 45 minutes before surgery. With the patient in the supine position, bilateral ultrasound-guided erector spinae plane block (ESPB) will be performed. A total volume of 60 mL of 0.25% bupivacaine (30 mL per side) will be injected. General anesthesia will then be administered according to standard practice. In the postoperative period, additional analgesia will be provided using intravenous morphine patient-controlled analgesia (PCA).
Sponsors
Leads: Karabuk University

This content was sourced from clinicaltrials.gov