Endoscopy Clinical Trials

Clinical trials related to Endoscopy Procedure

COMPARISON OF HEMODYNAMIC EFFECTS OF NALBUPHINE VERSUS FENTANYL: A RANDOMIZED, DOUBLE-BLINDED INTERVENTIONAL STUDY IN PATIENTS ON CARDIOPULMONARY BYPASS AT RAWALPINDI INSTITUTE OF CARDIOLOGY, RAWALPINDI

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

Participants will undergo routine pre-operative evaluation. An intravenous line will be placed in the recovery area. On arrival in the operating room, standard monitoring (blood pressure, heart rate, oxygen saturation, ECG, breathing monitor, and temperature) will be applied. A central venous catheter and an arterial line will be inserted under local anesthesia using sterile technique. Before anesthesia induction, patients will receive premedication including midazolam and an opioid pain-relief injection given slowly through the vein. General anesthesia will then be induced with etomidate. After adequate sedation, a muscle relaxant (atracurium) will be administered, and the patient will be ventilated with 100% oxygen using a face mask. The breathing tube will then be inserted and correct placement confirmed. During surgery, anesthesia will be maintained with oxygen, sevoflurane gas, and a continuous atracurium infusion. Hemodynamic parameters such as heart rate and blood pressure will be monitored throughout the peri-intubation and intraoperative period.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 60
Healthy Volunteers: t
View:

• Weighing 40-70kg

‣ ASA III of either sex

⁃ Undergoing cardiac surgery with CPB

Locations
Other Locations
Pakistan
Deparment of Anesthesia, Rawalpindi Institute of Cardiology, Rawalpindi
RECRUITING
Rawalpindi
Contact Information
Primary
Ayemon Principal Investigator, MBBS
ayemonfatima@gmail.com
+923211579066
Time Frame
Start Date: 2026-02-21
Estimated Completion Date: 2026-05-21
Participants
Target number of participants: 98
Treatments
Active_comparator: Group Nalbuphine
Participants will receive an injection of nalbuphine 0.2 mg/kg intravenous slowly over 5 minutes before induction.
Active_comparator: Group Fentanyl
Participants will receive an injection of fentanyl 3 µg/kg intravenous slowly over 5 min before induction.
Related Therapeutic Areas
Sponsors
Leads: Rawalpindi Institute of Cardiology

This content was sourced from clinicaltrials.gov