Endoscopy Clinical Trials

Clinical trials related to Endoscopy Procedure

A Randomized Controlled Trial Comparing Transcriptomic Profile Changes Following Carbon Dioxide (CO2) Laser Wedge Resection Versus Radial Incision for Benign Tracheal Stenosis

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Some people develop a narrowing of their windpipe (trachea), called benign tracheal stenosis, which can make it hard to breathe. Doctors often treat this by using a bronchoscope-a thin, flexible tube with a camera-to open up the airway or remove scar tissue. While these procedures help patients breathe better, we do not fully understand why the narrowing occurs or how the tissue heals afterward. The purpose of this study is to better understand the biological changes in the airway tissue before and after these standard medical procedures. During the procedure, small samples of tissue that would already be collected as part of normal care will be analyzed in the laboratory. The results may help doctors learn more about airway healing and could guide better treatments in the future.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• symptomatic tracheal stenosis

• idiopathic subglottic stenosis

• iatrogenic tracheal stenosis from intubation or tracheostomy

Locations
United States
Maryland
University of Maryland
RECRUITING
Baltimore
Contact Information
Primary
Chenchen Zhang, MD
chenchen.zhang@som.umaryland.edu
410-328-8138
Time Frame
Start Date: 2026-05-01
Estimated Completion Date: 2032-05-01
Participants
Target number of participants: 40
Treatments
Experimental: Carbon dioxide (CO2) laser wedge resection
Active_comparator: Radial incision and dilation
Related Therapeutic Areas
Sponsors
Leads: University of Maryland, Baltimore

This content was sourced from clinicaltrials.gov