Endoscopy Clinical Trials

Clinical trials related to Endoscopy Procedure

Effects of Preoperative Ultrasound-Guided Popliteal Sciatic and Saphenous Nerve Blocks on Early Pain and Functional Recovery After Ankle Arthroscopy: A Randomized, Double-Blind, Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This randomized, double-blind controlled trial investigates the effectiveness and potential trade-offs of preoperative ultrasound-guided popliteal sciatic and saphenous nerve blocks in patients undergoing ankle arthroscopy, a procedure often performed in day-case settings but associated with significant early postoperative pain and frequent opioid use. The study evaluates whether these nerve blocks can reduce early postoperative pain-measured by the highest NRS score within 24 hours-and examines their impact on functional recovery, including motor strength and ambulation. All patients receive standardized general anesthesia and multimodal analgesia, with outcomes including opioid consumption, ankle weakness, patient satisfaction, range of motion, muscle strength, hospital stay duration, and analgesia-related costs.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• Age between 18 and 65 years

• ASA physical status classification I-II

• Scheduled to undergo ankle arthroscopy under general anesthesia

• Expected to be available for follow-up on the day of surgery (day-case or short-stay surgery)

• Able to understand the procedures and methods of the clinical trial and voluntarily provide written informed consent

• Body mass index (BMI) between 16 and 32 kg/m²

Locations
Other Locations
China
The Second Affiliated Hospital Zhejiang University School of Medicine
RECRUITING
Hangzhou
Contact Information
Primary
zongyou Pan, Doctoral degree
panzongyou@gmail.com
86-19857004757
Time Frame
Start Date: 2026-01-30
Estimated Completion Date: 2026-12-30
Participants
Target number of participants: 70
Treatments
Experimental: PNB group
Prior to anesthesia induction, patients received nerve blocks in the anesthesia preparation room. In the prone position, under ultrasound guidance, the anesthesiologist performed a sciatic nerve block with 20 mL and a saphenous nerve block with 10 mL of 0.25% ropivacaine, for a total volume of 30 mL. The success of the block was assessed by the anesthesiologist based on circumferential spread of the local anesthetic around the target nerves under ultrasound, along with sensory reduction over the dorsum and plantar surface of the foot, the lateral foot, and the area around the Achilles tendon.
Placebo_comparator: placebo group
In the control group, the procedure was identical, except that an equal volume of 0.9% saline was administered in place of ropivacaine.
Related Therapeutic Areas
Sponsors
Leads: Second Affiliated Hospital, School of Medicine, Zhejiang University

This content was sourced from clinicaltrials.gov