Endoscopy Clinical Trials

Clinical trials related to Endoscopy Procedure

Determination of the Median Effective Volume (ED50) of Bupivacaine for Serratus Posterior Superior Intercostal Plane Block in Patients Undergoing Video-Assisted Thoracoscopic Surgery Using the Dixon Up-and-Down Method

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study aims to determine the minimum effective volume of bupivacaine required for the serratus posterior superior intercostal plane (SPSIP) block in patients undergoing video-assisted thoracoscopic surgery (VATS). The SPSIP block is an ultrasound-guided regional anesthesia technique used to provide postoperative pain relief after thoracic surgery. Using a stepwise dose-adjustment method, the volume of local anesthetic will be increased or decreased based on the effectiveness of the block in each patient. The main outcome of the study is to identify the volume that provides effective pain control in 50% of patients. The results may help optimize pain management while minimizing drug exposure.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age 18 years or older

• Scheduled for elective video-assisted thoracoscopic surgery (VATS)

• American Society of Anesthesiologists (ASA) physical status I-III

• Planned to receive ultrasound-guided serratus posterior superior intercostal plane block for postoperative analgesia

• Ability to provide written informed consent

Locations
Other Locations
Turkey
T.C. Sağlık Bakanlığı Bursa Şehir Hastanesi
RECRUITING
Bursa
Contact Information
Primary
emre ulusoy
emreulusoy36@gmail.com
+905379492799
Time Frame
Start Date: 2026-03-15
Estimated Completion Date: 2026-07-15
Participants
Target number of participants: 27
Treatments
Experimental: Serratus Posterior Superior Intercostal Plane Block (SPSIPB)
Participants receive an ultrasound-guided serratus posterior superior intercostal plane block (SPSIPB) with 0.5% bupivacaine before video-assisted thoracoscopic surgery (VATS). The injected volume is determined using the Dixon up-and-down sequential allocation method, starting from an initial volume and adjusted by 2 mL increments or decrements based on block success or failure in the preceding patient. Block success is assessed by a blinded outcome assessor according to predefined analgesic criteria.
Related Therapeutic Areas
Sponsors
Collaborators: Emre ULUSOY
Leads: Bursa City Hospital

This content was sourced from clinicaltrials.gov