Endoscopy Clinical Trials

Clinical trials related to Endoscopy Procedure

Comparison of the Effectiveness of Intravenous Analgesia Protocols Used After the Duration of Block Action for Postoperative Pain Control in Thoracic Surgery

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this study is to compare the effectiveness of three different intravenous (IV) patient-controlled analgesia (PCA) regimens-Fentanyl, Tramadol, and Ibuprofen-in managing postoperative pain and respiratory performance in patients undergoing Video-Assisted Thoracoscopic Surgery (VATS). While regional blocks like Erector Spinae Plane (ESP) block provide effective early analgesia, their effect typically diminishes after 8-12 hours, leading to potential 'rebound pain.' This study specifically investigates the period following the duration of the regional block's action. The primary goal is to evaluate which IV PCA protocol better controls pain (Visual Analog Scale scores) and supports better respiratory performance (measured by incentive spirometry) during the first 72 hours post-surgery

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• \- Patients aged 18 to 80 years.

• \- ASA (American Society of Anesthesiologists) Physical Status Score of I-III.

• \- Body Mass Index (BMI) between 18 and 35 kg/m².

• \- Undergoing elective thoracic surgery via Video-Assisted Thoracoscopic Surgery (VATS).

• \- Voluntary participation confirmed by signing the written Informed Consent Form.

Locations
Other Locations
Turkey
Ankara Etlik City Hospital, Department of Anesthesiology and Reanimation
RECRUITING
Ankara
Contact Information
Primary
Baris Turunc, MD
baris.turunc94@gmail.com
+90 5300202777
Backup
Dilek Unal, MD, Prof.
dilekunalmd@gmail.com
+90 5336957855
Time Frame
Start Date: 2026-06-02
Estimated Completion Date: 2026-10-15
Participants
Target number of participants: 135
Treatments
Experimental: Group F (Fentanyl Group)
Patients in this group are assigned to receive intravenous (IV) Patient-Controlled Analgesia (PCA) using a fentanyl solution. The treatment is initiated either at the 6th postoperative hour or upon the first request for analgesia (VAS \>4). This arm is the potent opioid-based treatment group.
Experimental: Group T (Tramadol Group)
Patients in this group are assigned to receive IV PCA using a tramadol solution. Similar to Group F, the protocol is initiated at the 6th postoperative hour or at the first analgesic demand. This arm represents the weak opioid-based approach.
Experimental: Group I (Ibuprofen Group)
Patients in this group are assigned to receive IV PCA using an ibuprofen solution. Similar to Group F and T, the protocol is initiated at the 6th postoperative hour or at the first analgesic demand. This arm is the non-opioid, NSAID-based treatment group.
Related Therapeutic Areas
Sponsors
Leads: Ankara Etlik City Hospital

This content was sourced from clinicaltrials.gov