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Comparison of the Effects of Serratus Posterior Superior Intercostal Plane Block and Intrathecal Morphine on Postoperative Acute Pain in Patients Undergoing Video-assisted Thoracoscopic Surgery

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study aims to compare the analgesic effects of the serratus posterior superior intercostal plane block and intrathecal morphine in patients undergoing video-assisted thoracoscopic surgery. This is a prospective, randomized, controlled, single-center clinical trial including adult patients undergoing elective thoracoscopic surgery. Participants will be randomly assigned to receive either a serratus posterior superior intercostal plane block or intrathecal morphine before general anesthesia. The primary outcome is cumulative opioid consumption during the first 24 postoperative hours, expressed as intravenous morphine milligram equivalents. Secondary outcomes include pain scores, time to first analgesic request, quality of recovery, and postoperative complications. The study aims to determine whether these two techniques differ in their effectiveness for postoperative pain management.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• Age between 18 and 75 years

• American Society of Anesthesiologists physical status I to III

• Scheduled for elective video-assisted thoracoscopic surgery including wedge resection, segmentectomy, or lobectomy

Locations
Other Locations
Turkey
Ondokuz Mayis University
RECRUITING
Atakent
Contact Information
Primary
Cengiz Kaya, Prof Dr
cengiz.kaya@omu.edu.tr
+905056793359
Time Frame
Start Date: 2026-04-15
Estimated Completion Date: 2026-09-30
Participants
Target number of participants: 60
Treatments
Experimental: Intrathecal Morphine
Participants receive intrathecal morphine before induction of general anesthesia. Intrathecal morphine is administered at a dose of 5 micrograms per kilogram in 3 milliliters of saline via spinal injection. All patients subsequently undergo standardized general anesthesia and receive postoperative patient-controlled analgesia with intravenous morphine.
Experimental: Serratus Posterior Superior Intercostal Plane Block
Participants receive an ultrasound-guided serratus posterior superior intercostal plane block before induction of general anesthesia. A total of 30 milliliters of 0.25 percent bupivacaine with epinephrine is administered into the interfascial plane between the serratus posterior superior muscle and intercostal muscles. All patients subsequently undergo standardized general anesthesia and receive postoperative patient-controlled analgesia with intravenous morphine.
Related Therapeutic Areas
Sponsors
Leads: Ondokuz Mayıs University

This content was sourced from clinicaltrials.gov

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