Endoscopy Clinical Trials

Clinical trials related to Endoscopy Procedure

Comparison of Mechanical Power in Pressure-Regulated Volume Control and Volume-Controlled Ventilation Modes During Laparoscopic Cholecystectomy

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study investigates how different breathing machine (ventilator) settings affect the energy delivered to the lungs during surgery. Mechanical power is a measure of this energy, and high levels can sometimes lead to lung irritation. In clinical practice, a mode called Pressure-Regulated Volume Control (PRVC) is often used because it lowers the peak pressure in the airways, which is generally thought to be safer. However, doctors have noticed that even though the peak pressure goes down in PRVC mode, the total mechanical power displayed on the monitor might actually increase compared to the standard Volume-Controlled Ventilation (VCV) mode. In this study, patients undergoing gallbladder surgery will be monitored using both ventilation modes in a random order. The researchers will compare the machine-calculated mechanical power for both modes to see if the perceived benefit of lower peak pressure in PRVC actually results in lower overall energy transfer to the lungs.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• Patients undergoing elective laparoscopic cholecystectomy surgery.

• Patients between 18 and 75 years of age.

• American Society of Anesthesiologists (ASA) physical status I, II or III.

• Body Mass Index (BMI) between 18.5 and 35 kg/m².

• Voluntary written informed consent for participation.

Locations
Other Locations
Turkey
Dr. Abdurrahman Yurtaslan Ankara Oncology Hospital
RECRUITING
Yenimahalle
Contact Information
Primary
arif timuroglu, MD
ariftimuroglu@yahoo.com
+905072601980
Time Frame
Start Date: 2026-07-01
Estimated Completion Date: 2026-08-12
Participants
Target number of participants: 80
Treatments
Experimental: group A; VCV First, Then PRVC
Following the stabilization of pneumoperitoneum, participants will be ventilated using the Volume-Controlled Ventilation (VCV) mode for 10 minutes. At the end of this period, respiratory data and mechanical power values will be recorded. Immediately after, the ventilator will be switched to the Pressure-Regulated Volume Control (PRVC) mode with equivalent settings. After another 10-minute stabilization period in PRVC mode, a second set of measurements will be recorded.
Experimental: group B; PRVC First, Then VCV
Following the stabilization of pneumoperitoneum, participants will be ventilated using the Pressure-Regulated Volume Control (PRVC) mode for 10 minutes. At the end of this period, respiratory data and mechanical power values will be recorded. Immediately after, the ventilator will be switched to the Volume-Controlled Ventilation (VCV) mode with equivalent settings. After another 10-minute stabilization period in VCV mode, a second set of measurements will be recorded.
Related Therapeutic Areas
Sponsors
Leads: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

This content was sourced from clinicaltrials.gov