Intraoperative Autonomic Blockade to Prevent Early Postoperative Pain After Laparoscopic Cholecystectomy: A Double-Blind, Randomized Controlled Trial
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
This study proposes infiltrating the hepatoduodenal ligament and the serosal reflection of the gallbladder cystic plate with a combination of Bupivacaine (a long-acting local anesthetic) and Dexamethasone (a corticosteroid). This technique aims to block the hepatic branches of the celiac plexus to improve visceral pain control and its associated clinical manifestations, reduce analgesic requirements, and lower readmission rates, thereby facilitating recovery.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Elective or emergency laparoscopic cholecystectomy for cholelithiasis with or without cholecystitis.
Locations
Other Locations
Colombia
clinica Iberoamerica
RECRUITING
Barranquilla
Clinica Portoazul
RECRUITING
Barranquilla
Contact Information
Primary
Jorge Daes, MD
jorgedaez@gmail.com
+573106363636
Backup
Andres Hanssen, MD
anhanssen@gmail.com
+573123012321
Time Frame
Start Date: 2025-01-15
Estimated Completion Date: 2025-11-04
Participants
Target number of participants: 60
Treatments
Experimental: Autonomic Neural Blockade
This group will receive the Autonomic nerve block performed with:~* Bupivacaine: 20 mL of 0.5%.~* Dexamethasone: 8 mg. Procedure: Percutaneous injection under direct laparoscopic visualization into the hepatoduodenal ligament and the visceral peritoneal reflection.
No_intervention: NO BLOCKADE
Patients will undergo a laparoscopic cholecystectomy without an autonomic neural blockade
Related Therapeutic Areas
Sponsors
Leads: Universidad Simón Bolívar