Evaluation of the Effects of Preoperative Erector Spinae Plane Block Combined With Low-Flow Anaesthesia on Postoperative Quality of Recovery and Opioid Consumption: A Prospective, Randomized, Controlled Study
Status: Recruiting
Location: See location...
Intervention Type: Drug, Other, Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This prospective randomized controlled study aims to evaluate the effects of preoperative ultrasound-guided erector spinae plane (ESP) block combined with low-flow anaesthesia on postoperative quality of recovery and opioid consumption in patients undergoing elective laparoscopic cholecystectomy. The study will compare postoperative recovery quality, pain scores, analgesic requirements, and perioperative outcomes between patients receiving ESP block with low-flow anaesthesia and those receiving standard anaesthetic management.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:
• Patients aged 18-65 years
• ASA physical status I-II
• Body mass index (BMI) \<35 kg/m²
• Scheduled for elective laparoscopic cholecystectomy
• Ability to provide written informed consent
Locations
Other Locations
Turkey
Taksim Training and Research Hospital
RECRUITING
Istanbul
Contact Information
Primary
Leyla Sivacigil, MD
veralleyla@hotmail.com
90 5065983478
Backup
Celal Kaya, MD
celalmadime@gmail.com
90 5435176760
Time Frame
Start Date: 2026-06-18
Estimated Completion Date: 2027-06-18
Participants
Target number of participants: 72
Treatments
Active_comparator: ESPB + Standard-Flow Anaesthesia
Participants will receive a preoperative bilateral ultrasound-guided ESPB with 20 mL of 0.25% bupivacaine on each side at the T7-T8 level, in addition to standard-flow sevoflurane anaesthesia during elective laparoscopic cholecystectomy. Fresh gas flow will be maintained at 3 L/min during the maintenance phase of anaesthesia.
Experimental: ESPB + Low-Flow Anaesthesia
Participants will receive a preoperative bilateral ultrasound-guided ESPB with 20 mL of 0.25% bupivacaine on each side at the T7-T8 level, in addition to low-flow sevoflurane anaesthesia during elective laparoscopic cholecystectomy. Following induction, fresh gas flow will be reduced to 0.5 L/min during the maintenance phase of anaesthesia.
Related Therapeutic Areas
Sponsors
Leads: Taksim Egitim ve Arastirma Hastanesi