Whole Course Multi-model Prehabilitation to Improve Clinical Outcome in Patients Undergoing Neoadjuvant Treatment Prior to Gastrectomy : A Single Center Randomized Control Trial
The intention of research is to establish a multimodal prehabilitation protocol in patients who undergo neoadjuvant chemotherapy prior to gastrectomy, explore the feasibility and effectiveness of the measures and evaluate the effect of program on short-term clinical outcome, fitness and long-term prognosis.
• Aged ≥18 years;
• Eastern Cooperative Oncology Group (ECOG) performance status score ≤2；
• Endoscopic biopsies were pathologically confirmed as gastric adenocarcinoma；
• The feasibility of neoadjuvant therapy was suggested by MDT, and the feasibility of radical gastrectomy was re-evaluated after neoadjuvant therapy;
• Blood routine, liver function, kidney function, heart function and lung function were normal before neoadjuvant therapy, and there was no contraindication of chemotherapy and surgery;
• The pregnancy test was negative within 1 month, and she was not pregnant or breastfeeding;
• Informed consent and ability to comply with research protocols.