Gastrectomy Clinical Trials

Clinical trials related to Gastrectomy Procedure

Effect of Lidocaine Applied Via Nasogastric Tube on Postoperative Nausea and Vomiting in Obese Patients Undergoing Bariatric Surgery

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn if intragastric administration of lidocaine can reduce postoperative nausea and vomiting in obese patients undergoing laparoscopic sleeve gastrectomy. The main question it aims to answer is: Does administering 0.5% lidocaine via an orogastric tube reduce the incidence of postoperative nausea and vomiting (PONV) in the post-anesthesia care unit and within the first 24 hours after surgery compared to a placebo (normal saline)? Researchers will compare the Lidocaine Group to the Placebo Group to see if the intervention lowers the PONV incidence. Participants will: * Receive the assigned study solution (either 0.5% lidocaine 20ml or normal saline 20ml) through an orogastric tube upon surgery completion and before extubation. * Have their gastric tube clamped for 5 minutes to ensure mucosal exposure before removal. * Undergo standardized total intravenous anesthesia and perioperative management according to the study protocol. * Be assessed for nausea, vomiting, and other outcomes at specified time points postoperatively in the recovery room and at 6, 12, and 24 hours.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• Adults aged between 18 and 65 years old;

• American Society of Anesthesiologists (ASA) physical status classification II - III;

• Planned to undergo primary elective laparoscopic sleeve gastrectomy with general anesthesia;

• Capable of giving informed consent.

Locations
Other Locations
China
General Hospital of Ningxia Medical University
RECRUITING
Yinchuan
Contact Information
Primary
Siying He
1342850868@qq.com
+86 18209610221
Time Frame
Start Date: 2026-05-20
Estimated Completion Date: 2027-06-30
Participants
Target number of participants: 100
Treatments
Experimental: Lidocaine
Lidocaine is administered via a gastric tube.
Experimental: Normal Saline
Administer normal saline through the gastric tube.
Related Therapeutic Areas
Sponsors
Leads: General Hospital of Ningxia Medical University

This content was sourced from clinicaltrials.gov