A Multi-center, Feasibility Study to Evaluate the Use and Safety and of the Pediatric PUMA-G System for Percutaneous Ultrasound Gastrostomy

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this research study is to test a new device called the PUMA-G Pediatric System. The research will measure if the device works well to safely aid doctors placing gastrostomy feeding tubes in children. The PUMA-G Pediatric System is an investigational device that uses ultrasound and magnets to guide insertion of a feeding tube.

Eligibility
Participation Requirements
Sex: All
Maximum Age: 21
Healthy Volunteers: f
View:

• Informed consent must be obtained from the patient or a Legally Authorized Representative (ex. parent/guardian) before any study-specific assessment is performed

• Weight ≥5 (Phase 0, Phase 1, Phase 2)

• Weight ≥3kg and \<10kg (Phase 3)

• Estimated abdominal wall thickness ≤3cm

• Indication for gastrostomy tube placement, with or without jejunal access tubing via gastrostomy tract, determined to be present for any of the following reasons:

• Anatomic: Ear, nose, or throat abnormalities (Pierre-Robin sequence cleft lip palate)

• Neurologic: Head trauma, Cerebral palsy

• Bowel Disease: Short Bowel syndrome, intestinal dysmotility, inflammatory bowel disease, malabsorption

• Failure to Thrive: Cystic Fibrosis, Cholestasis, AID, Chronic renal failure, and food refusal

• Patient determined to be an appropriate candidate for PUG, PEG, or PRG by the clinical care team

• Anticipated discharge \> 24 hrs following gastrostomy

Locations
United States
Washington, D.c.
Children's National Hospital
RECRUITING
Washington D.c.
New York
Nyph/Cumc
RECRUITING
New York
Pennsylvania
Children's Hospital Of Phildelphia
RECRUITING
Philadelphia
Contact Information
Primary
Jack Kent, MPH
jack@coaptech.com
4102151638
Backup
Steven Tropello, MD
steven@coaptech.com
4348255184
Time Frame
Start Date: 2023-07-07
Estimated Completion Date: 2024-12-31
Participants
Target number of participants: 80
Treatments
Experimental: Percutaneous Ultrasound Gastrostomy (PUG)
Enrolled subjects will receive the PUG procedure using the PUMA-G Pediatric System performed by an Interventional Radiologist
No_intervention: Percutaneous Radiologic Gastrostomy
A matched, retrospective control cohort of patients previously admitted to hospital for the placement of gastrostomy tubes by Interventional Radiology will be used to compare performance of the PUMA-G Pediatric System to standard of care.
Related Therapeutic Areas
Sponsors
Collaborators: Columbia University, Children's National Research Institute, Children's Hospital of Philadelphia
Leads: CoapTech

This content was sourced from clinicaltrials.gov