CABGpreHAB- Home-based Multimodal Prehabilitation (CABGpreHAB) for Elective Patients Awaiting CABG-surgery - a Feasibility Study Protocol

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Patients with ischemic heart disease (IHD) awaiting coronary artery bypass graft (CABG) surgery often face challenges like advanced age, frailty, comorbidities, and physical inactivity. These factors, combined with the physiological and psychological stress of surgery, can hinder postoperative recovery. Traditionally, strategies to improve surgical outcomes focus on the intra- and postoperative periods. However, the pre-surgery waiting period offers a window of opportunity for prehabilitation, which aims to enhance patients' functional capacity through exercise, nutrition, and psychological support. The CABGpreHAB feasibility study evaluates the feasibility of a home-based multimodal prehabilitation intervention for patients awaiting elective CABG surgery. This randomized pilot study compares the intervention plus usual care to usual care alone, assessing feasibility outcomes like recruitment, retention, attrition, fidelity, and adherence. The study aims to optimize a subsequent full-scale randomized controlled trial (RCT) and improve patient outcomes by leveraging the pre-surgery period for prehabilitation.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Planned to have elective isolated first-time CABG surgery.

• 18 years or older

• Two weeks or more before surgery

• Speaks and understands Danish.

• Gives written informed consent.

Locations
Other Locations
Denmark
The Department of Heart and Lung Surgery, Copenhagen University hospital Rigshospitalet
RECRUITING
Copenhagen
Contact Information
Primary
Dorte Baek Olsen, PhD student
dorte.baek.olsen@regionh.dk
+4526625705
Time Frame
Start Date: 2025-06-24
Estimated Completion Date: 2026-07-18
Participants
Target number of participants: 50
Treatments
Experimental: CABGpreHAB multimodal prehabilitation intervention + usual care
Patients randomized to the multimodal prehabilitation programme will, besides usual care, receive home-based preoperative interventions that consist of:~Web-based exercise intervention supervised by skilled physiotherapists and delivered via a tablet. Each session lasts 60 minutes, three times per week for the prehabilitation period. Patients will be instructed to perform daily exercise tasks such as brisk walking and sit-to-stand exercises.~Phone call and consultation delivered by a specialised nurse once a week. This consultation will deliver psychosocial support, equipping patients with coping strategies to mitigate stress, anxiety, and depression. Furthermore, nutritional advice will take place at these consultations, as well as advice on smoking cessation and alcohol cessation.
Other: Control group
Participants assigned to the control group will receive usual care.
Related Therapeutic Areas
Sponsors
Leads: Rigshospitalet, Denmark

This content was sourced from clinicaltrials.gov