Heart Bypass Surgery Clinical Trials

Clinical trials related to Heart Bypass Surgery Procedure

Surgical Techniques to Prevent Perioperative Neurologic Complications in Patients Undergoing Coronary Artery Bypass Grafting

Status: Recruiting
Location: See all (4) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

To explore surgical strategies that reduce perioperative neurologic complications in cardiovascular surgery, with the aim of improving perioperative outcomes and quality of life while reducing the socioeconomic burden. Specifically: This multicenter, randomized controlled clinical trial will evaluate the benefits of a novel aortic no-touch technique in reducing perioperative silent brain infarction(SBI) among patients undergoing surgical treatment for coronary artery disease. The findings are expected to provide a safe and effective myocardial revascularization strategy for individuals at high risk of cerebral ischemia.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Adult patients (\>18 years old) with multivessel coronary artery disease who are scheduled to undergo isolated off-pump coronary artery bypass grafting and who provide informed consent to participate in this study.

Locations
Other Locations
China
Fuwai Hospital Chinese Academy of Medical Sciences
RECRUITING
Beijing
Peking University First Hospita
NOT_YET_RECRUITING
Beijing
Qingdao Cardiovascular Hospital
NOT_YET_RECRUITING
Qingdao
Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen
NOT_YET_RECRUITING
Shenzhen
Contact Information
Primary
Lianxin Chen
chenlianx1@163.com
01088322265
Time Frame
Start Date: 2026-03-10
Estimated Completion Date: 2028-06-30
Participants
Target number of participants: 380
Treatments
Active_comparator: Traditional off-pump coronary artery bypass grafting (Ao-SVG)
Off-pump CABG with proximal saphenous vein graft (SVG) anastomoses constructed on the ascending aorta using a partial-occlusion (side-biting) clamp.
Experimental: Aortic no-touch coronary artery bypass grafting (RIMA-SVG)
Aortic no-touch off-pump CABG in which the saphenous vein graft (SVG) is anastomosed to the right internal mammary artery (RIMA) as a composite graft, avoiding any clamping or manipulation of the ascending aorta.
Sponsors
Leads: China National Center for Cardiovascular Diseases

This content was sourced from clinicaltrials.gov