Effect of Resistance Training on Functional Capacity, Quality of Life and Cardiac Biomarkers in Patients on the Waiting List for Heart Transplant: a Randomized and Controlled Clinical Trial
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The present longitudinal, randomized, and blinded clinical trial aims to: * Evaluate the effects of resistance training on the functional capacity, quality of life, and cardiac biomarkers of hospitalized patients with heart failure (HF) on the waiting list for heart transplantation (HTx). * Evaluate the associations between Fried's frailty classification and functional capacity responses to resistance training. The protocol will have a total duration of 12 weeks.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:
• patients included in heart transplant list ≤1 month
• hemodynamically stable in the last 48 hours defined as mean arterial pressure (MAP) ≥ 60 mmHg and ≤ 120 mmHg and - Heart rate (HR) ≥ 60 bpm and ≤ 120 mmHg.
• dobutamine dose ≤ 10 mcg/kg/min
Locations
Other Locations
Brazil
Instituto do Coração - Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
RECRUITING
São Paulo
Contact Information
Primary
Juliana A Nascimento, PT, PhD
juliana.nascimento@fm.usp.br
+55 11 30618529
Backup
Rafael M Ianotti, PT
rafael.ianotti@hc.fm.usp.br
+55 11 26615319
Time Frame
Start Date: 2024-06-18
Estimated Completion Date: 2026-11-30
Participants
Target number of participants: 50
Treatments
Experimental: Resistance Training Group
Patients will receive the standard treatment provided by the hospital inpatient unit alongside the resistance training program.
Active_comparator: Standard Treatment Group
Patients will receive the standard treatment provided by the hospital inpatient unit.
Related Therapeutic Areas
Sponsors
Leads: University of Sao Paulo General Hospital
Collaborators: Conselho Nacional de Desenvolvimento Científico e Tecnológico