Intra-operative Use of Ketamine for Post-Operative Analgesia in Patients Undergoing Hemorrhoidectomy: A Prospective, Randomized Controlled Trial.
Who is this study for? Patients with Hemorrhoids
What treatments are being studied? Ketamine
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
This is a prospective, randomized study of ketamine versus no ketamine in approximately 100 patients undergoing hemorrhoidectomy for Grade III or IV hemorrhoids. The participants will be blinded to which treatment arm they are assigned, because participants will be under anesthesia when the ketamine is administered. The investigators will know whether the participant receives ketamine or not.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 100
Healthy Volunteers: f
View:
• Adults aged 18-100
• Undergoing a hemorrhoidectomy for Grade III or IV hemorrhoids.
Locations
United States
Oklahoma
University of Oklahoma Health Sciences Center
RECRUITING
Oklahoma City
Contact Information
Primary
Steven N Carter, MD
steven-carter@ouhsc.edu
405-271-8001
Time Frame
Start Date: 2020-06-15
Estimated Completion Date: 2025-07
Participants
Target number of participants: 100
Treatments
Active_comparator: Intraoperative ketamine infusion
Subjects in this group will receive standard anesthesia during surgery and a dose of ketamine at 0.3 mg/kg IV bolus prior to surgical incision. If the procedure lasts more than 1 hour, an additional bolus dose will be given.
No_intervention: Control group
This group will only receive the standard anesthesia during surgery with no ketamine.
Related Therapeutic Areas
Sponsors
Leads: University of Oklahoma