Development and Validation of Novel Models Including Tumor Micronecrosis for Predicting the Postoperative Survival of Patients With Hepatocellular Carcinoma
Status: Unknown
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
The heterogeneity of hepatocellular carcinoma (HCC) leads to the unsatisfying predicting performance of current staging systems. HCC patients with pathological tumor micronecrosis have immunosuppressive microenvironment. We aimed to develop novel prognostic models by integrating micronecrosis to more precisely predict the survival of HCC patients after hepatectomy.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 90
Healthy Volunteers: f
View:
• pathologically diagnosed as HCC;
• curative hepatectomy with R0 resection;
• conserved liver function with Child Pugh class A or B
Locations
Other Locations
China
the First Affiliated Hospital, School of Medicine, Zhejiang University
RECRUITING
Hangzhou
Contact Information
Primary
Tingbo Liang, PhD
liangtingbo@zju.edu.cn
Backup
Qi Zhang, MD
qi.zhang@zju.edu.cn
13819137113
Time Frame
Start Date: 2022-09-15
Completion Date: 2023-12-30
Participants
Target number of participants: 765
Treatments
training cohort
HCC patients receiving curative hepatic resection
validation cohort
HCC patients receiving curative hepatic resection
Related Therapeutic Areas
Sponsors
Leads: Zhejiang University