Postoperative Heme Oxygenase Induction and Carbon Monoxide Production as a Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
the investigators will pursue two specific aims: (1) to monitor the extent of heme oxygenase induction (by measuring endogenous CO production) in relationship to the extent of hepatic resection (2) to assess the production of CO in patients following liver resection and correlate these findings to the rate of liver regeneration and liver function.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Patient plans to have partial liver resection for primary liver pathology or metastatic disease
• Patient is able to comprehend and willing to sign the written consent form
Locations
United States
New Jersey
Englewood Hospital
RECRUITING
Englewood
Contact Information
Primary
Jamie Ketas
jamie.ketas@ehmchealth.org
2018943418
Backup
Raquel Molina
raquel.molina@ehmchealth.org
Time Frame
Start Date: 2025-11-21
Estimated Completion Date: 2039-01-01
Participants
Target number of participants: 125
Treatments
Experimental: all participants
all participants will provide breath samples to detect carbon monoxide levels
Related Therapeutic Areas
Sponsors
Leads: Englewood Hospital and Medical Center