Low Calorie Diet Before Liver Surgery - A Nordic Multicentre Randomized Controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The rationale for this study is to evaluate whether a standardized, preoperative, short-term Low Calorie Diet (LCD) reduces intraoperative bleeding and postoperative morbidity in liver surgery. Participants with a BMI of 30 or higher, scheduled for liver surgery, if accepting participation, will be randomized to a 7 day LCD or no intervention. A previous small single center RCT have shown significantly reduced intraoperative blood loss and a tendency towards less postoperative complications. This multi-centre study aims to include enough patients with power to analyze also postoperative complications.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Scheduled for open or minimally invasive liver resection
• BMI ≥30
Locations
Other Locations
Sweden
Department och Surgery, Skane University Hospital
RECRUITING
Lund
Contact Information
Primary
Jenny L Rystedt, MD, PhD
jenny.rystedt@med.lu.se
+46705124336
Backup
Helena Taflin, MD, PhD
helena.taflin@vgr.se
Time Frame
Start Date: 2026-06-01
Estimated Completion Date: 2029-07-01
Participants
Target number of participants: 200
Treatments
No_intervention: Standard
Liver surgery standard of care
Experimental: Intervention
LCD
Related Therapeutic Areas
Sponsors
Leads: Region Skane