The Effect of Celecoxib on Heterotopic Bone Formation Following Cementless Total Hip Arthroplasty
Status: Unknown
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
The primary goal of this observational study is to demonstrate the incidence of heterotopic ossification (HO) in patients with cementless total hip joint replacement surgery over time and secondly, demonstrate the relationship between celecoxib and HO formation. Lastly, investigators will examine the relationship between HO and patient-reported outcome measures (PROMs).
Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:
• All primary total hip replacements with Cementless Tri-lock BPS (Depuy, Warsaw, IN) with minimum 2 years follow up.
Locations
Other Locations
Canada
Dr, Adam Hart
Montreal
Time Frame
Start Date: 2022-08-02
Completion Date: 2023-08
Participants
Target number of participants: 200
Treatments
Patients with and without HO before Celecoxib clinical pathway
Patients with and without heterotopic ossification (HO) before the clinical pathway was changed to include celecoxib following cementless total hip joint replacement surgery between periods 2009-2012.
Patients with and without HO after Celecoxib clinical pathway
Patients with and without heterotopic ossification (HO) after the clinical pathway was changed to include celecoxib following cementless total hip joint replacement surgery between periods 2013-2020.
Related Therapeutic Areas
Sponsors
Leads: McGill University Health Centre/Research Institute of the McGill University Health Centre