Pericapsular Nerve Block Versus Intrathecal Morphine for Analgesia After Primary Hip Arthroplasty: a Double Blind, Non-inferiority Study

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The aim of this clinical trial is to compare the analgesic effect of pericapsular nerve block (PENG) with intrathecal morphine in patients scheduled for total hip replacement surgery. The main question to be answered is whether the PENG block is equivalent to intrathecal morphine in reducing postoperative pain. Participants will be randomised into two groups. Patients assigned to the PENG group will receive spinal anaesthesia with local anaesthetic (isobaric bupivacaine) alone and a PENG block. Patients assigned to the intrathecal morphine (ITM) group will receive spinal anaesthesia with a mixture of local anaesthetic (isobaric bupivacaine) and morphine (100 mcg) and a sham PENG block to ensure patient blinding.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Male and female patients

• ASA (American Society of Anaesthesiologists) I-III

• 18 years of age or older

• Patients scheduled for elective primary hip arthroplasty

• Able to give written conformed consent autonomously

Locations
Other Locations
Switzerland
University Hospital of Lausanne
RECRUITING
Lausanne
Contact Information
Primary
Eric Albrecht, Prof
eric.albrecht@chuv.ch
+41795566341
Time Frame
Start Date: 2024-09-10
Estimated Completion Date: 2027-05-01
Participants
Target number of participants: 80
Treatments
Experimental: PENG group
Pericapsular nerve group block
Active_comparator: ITM group
intrathecal morphine injection
Related Therapeutic Areas
Sponsors
Leads: Centre Hospitalier Universitaire Vaudois

This content was sourced from clinicaltrials.gov

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