Hip Replacement Clinical Trials

Clinical trials related to Hip Replacement Procedure

GATOR: Geriatric Acetabular fracTures: Open Reduction Internal Fixation Versus Replacement - A Large Cohort of Acute Open Reduction Internal Fixation (ORIF) Versus Total Hip Arthroplasty for Geriatric Acetabular Fractures

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Management of acetabular (hip) fractures in the geriatric population can be very challenging because of pre-existing medical comorbidities, pre-existing osteoporosis and increased risk of mortality. The two most common treatment options for acetabular fractures are either surgical fixation using plates and screws to hold the fractured pieces in the correct position until the fracture has healed or surgical fixation in addition to a total hip replacement. Surgical fixation requires prolonged immobilization of the affected limb (typically around 6-12 weeks post-operatively), which can lead to disability and other complications. Such patients, especially those who are frail and cognitively impaired, are unable to adhere to the immobilization restrictions, leading to an increased risk of fixation failure. Patients who underwent open reduction internal fixation (ORIF) of an acetabular fracture were reported to have about 25 times greater incidence of hip replacement compared with general population matched controls. Additionally, performing a subsequent hip replacement after a previous surgical fixation (ORIF) of an acetabular fracture, especially in the elderly population, can present a number of technical difficulties including; difficult dissection due to previous incision(s) and scarring, dealing with retained hardware, bony deficiency and the possibility of infected hardware. The aim of the study is to perform a large cohort study to assess pain and physical function in patients 60 years and older who have sustained an acetabular fracture.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Healthy Volunteers: f
View:

• 60 years of age or older

• Isolated and Displaced (more or equal to 2mm on any radiographic view) fracture of the acetabulum

• Patient requires surgical treatment, either THA+ORIF or ORIF surgeries

• Fracture is acute (within 3 weeks of injury)

• Patient was ambulatory (with or without walking aids) prior to their acetabular fracture injury

• Patient is able to provide informed consent to participation in the study

• Patient is able to read and understand English

Locations
Other Locations
Canada
Unity Health Toronto - St Michael's Hospital
RECRUITING
Toronto
Contact Information
Primary
Cassandra Tardif-Theriault, BKin
cassandra.tardif-theriault@unityhealth.to
4168646060
Time Frame
Start Date: 2025-12
Estimated Completion Date: 2030-12
Participants
Target number of participants: 104
Treatments
Total hip arthroplasty + ORIF
Patients will receive acute primary total hip arthroplasty (THA) with open reduction internal fixation (ORIF) as a treatment for their acetabular fracture
Surgical Fixation (ORIF)
Patients will receive open reduction internal fixation (ORIF) as a treatment for their acetabular fracture
Related Therapeutic Areas
Sponsors
Leads: Unity Health Toronto

This content was sourced from clinicaltrials.gov