The Effect of Deep Versus Moderate Neuromuscular Blocking on Patients Undergoing Open Hysterectomy
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study aimed for Determination of the impacts of deep neuromuscular blockade (DNMB) on surgical outcomes, consumption of perioperative opioid analgesia, and serum levels of inflammatory cytokines in comparison to moderate NMB (MNMB).
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: f
View:
• Women who will be admitted to undergo elective hysterectomy
• ,-ASA grade I or II,
• Body mass index (BMI) of \<35 kg/m2
Locations
Other Locations
Egypt
Faculty of Medicine Menoufia University
RECRUITING
Menoufia
Contact Information
Primary
Rabab Habeeb, MD
rabab_habeeb@med.menofia.edu.eg
+201001970973
Time Frame
Start Date: 2026-02-01
Estimated Completion Date: 2026-09-01
Participants
Target number of participants: 88
Treatments
Active_comparator: MNMB
rocuronium will be given as 0.2 mg/kg to maintain a post-tetanic count (PTC) of \>1, and TOF in the range of
Active_comparator: DNMB
rocuronium infusion was used to provide 0.48-0.72 mg/kg/h to maintain PTC 0-1
Related Therapeutic Areas
Sponsors
Leads: Menoufia University