Effect of Terlipressin for Intraoperative Blood Pressure Management in Kidney Transplantation, a Double-blind Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Prospective double blind randomized controlled trial. By randomizing patients undergoing kidney transplantation into a conventional catecholamine drug (dobutamine) blood pressure maintenance group and a terlipressin-complexed dobutamine group, the investigators compared the effect of intraoperative blood pressure maintenance and the dosage of the vasoactive drug, postoperative graft function, delayed graft function, and other related complications between the two groups, in order to demonstrate whether the use of terlipressin for blood pressure regulation during kidney transplantation is superior to the existing treatments.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients with end-stage renal disease aged 18 years or above

Locations
Other Locations
China
Beijing Friendship Hospital
RECRUITING
Beijing
Contact Information
Primary
Wenhe Yang
13810673664@163.com
86 13810673664
Time Frame
Start Date: 2025-03-06
Estimated Completion Date: 2027-06
Participants
Target number of participants: 150
Treatments
No_intervention: dopamine
Continuous using of dopamine as blood pressure regulation after anesthesia, with dosage adjusted according to intraoperative needs
Experimental: terlipressin + dopamine
Terlipressin was given before the graft circulation was established while continuous using of dopamine during the whole operation
Related Therapeutic Areas
Sponsors
Leads: Beijing Friendship Hospital

This content was sourced from clinicaltrials.gov