A Prospective, Observational, Single-Center Study Evaluating Preoperative and Postoperative Changes in the Frontal QRS Axis on Electrocardiogram in Patients Undergoing Total Knee Arthroplasty Under Spinal Anesthesia
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
This prospective, single-center, observational study aims to evaluate changes in the frontal QRS axis on ECG before and after spinal anesthesia in patients undergoing total knee arthroplasty. The primary objective is to determine whether spinal anesthesia causes a significant alteration in the frontal QRS axis. A total of 80 patients will be enrolled, and preoperative and postoperative ECG measurements will be compared using paired t-test or Wilcoxon signed-rank test depending on data distribution.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 45
Maximum Age: 85
Healthy Volunteers: f
View:
• Aged between 45 and 85 years
• ASA physical status I-III
• Scheduled for elective total knee arthroplasty under spinal anesthesia
• Able to tolerate 12-lead ECG before and within 2 hours after surgery
Locations
Other Locations
Turkey
Elazığ Fethi Sekin City Hospital
RECRUITING
Elâzığ
Contact Information
Primary
Sevim Ş Karataş, MD
sevim.senolkaratas@saglik.gov.tr
+905325736611
Backup
Sait F Öner, MD
sfatihoner@gmail.com
+905336271358
Time Frame
Start Date: 2025-09-01
Estimated Completion Date: 2025-10-01
Participants
Target number of participants: 80
Treatments
TKA Patients
Patients undergoing elective total knee arthroplasty under spinal anesthesia. Frontal QRS axis will be measured using standard 12-lead ECG preoperatively (within 2 hours before surgery) and postoperatively (within 2 hours after surgery and before mobilization). The study aims to evaluate the change in frontal QRS angle following spinal anesthesia.
Related Therapeutic Areas
Sponsors
Leads: Sevim Şenol Karataş