A Pilot Study for a Novel and Personalized Voice Restoration Device for Patients With Laryngectomy

Status: Not_yet_recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The investigators will conduct a pilot experiment for a novel and personalized method for voice restoration using machine learning applied to surface EMG (sEMG) signal from articulatory muscles of the face and the neck allowing recognition of silent speech. The investigators predict that the use novel personalized method for voice restoration will be feasible and successful for patients.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 110
Healthy Volunteers: t
View:

⁃ Group A: Healthy Volunteers

• Adult subjects, 18 or older

• Without any voice impairments

⁃ Group B: Subjects with Aphonia or Dysphonia

• Adult subjects, 18 or older

• Documentation of severe dysphonia and/or aphonia, or a GRBAS score \> 0 (GRBAS is a scale that can be used to assess voice quality of subjects who do not have a recorded history of dysphonia or aphonia. The GRBAS scale evaluates for grade, roughness, breathiness, asthenia, and strain).

Locations
United States
New York
Weill Cornell Medicine
New York
Contact Information
Primary
Anais Rameau, M.D.
anr2783@med.cornell.edu
6469627464
Backup
Sara W Albert, B.A.
saa4056@med.cornell.edu
6469629883
Time Frame
Start Date: 2025-12-01
Completion Date: 2026-12
Participants
Target number of participants: 100
Treatments
Experimental: Patients with Aphonia or Dysphonia
Participants with Aphonia or Dysphonia will be asked to recite phrases with sEMG attached to articulatory muscles.
Placebo_comparator: Healthy Volunteers
Healthy Volunteer will be asked to recite phrases with sEMG attached to articulatory muscles.
Related Therapeutic Areas
Sponsors
Leads: Weill Medical College of Cornell University

This content was sourced from clinicaltrials.gov