Sun Yat-sen Memorial Hospital, Sun Yat-sen University

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this observational study is to assess the safety and efficacy of submental artery island flap (SMAIF) in the reconstruction of laryngeal and hypopharyngal defects after the surgical resection of hypopharyngeal cancer. The main questions it aims to answer are: * The survival of SMAIF and the recovery of laryngeal function. * The oncologic outcomes of SMAIF comparing with other reconstructions or radiotherapy. Participants will underwent partial laryngectomy and hypopharyngectomy and reconstruction of SMAIF. Postoperative adjuvant radiotherapy will be recommented when adverse pathologic features were noted.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• T2-T3 hypopharyngeal squamous cell carcinoma located in the piriform sinus or posterior hypopharyngeal wall cancer;

• The contralateral hemilarynx is mobile;

• the Eastern Cooperative Oncology Group (ECOG) performance status (PS) score was 0 or 1;

• Without a history of radiotherapy.

Locations
Other Locations
China
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
RECRUITING
Guangzhou
Contact Information
Primary
Renhui Chen, MD
chenrh23@mail.sysu.edu.cn
+862081332587
Backup
Liushan Ou, MD
sys_iit@163.com
+8681332587
Time Frame
Start Date: 2023-02-16
Estimated Completion Date: 2030-02-16
Participants
Target number of participants: 40
Treatments
Experimental: Submental artery flap reconstruction group
Related Therapeutic Areas
Sponsors
Leads: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

This content was sourced from clinicaltrials.gov