Lithotripsy Clinical Trials

Clinical trials related to Lithotripsy Procedure

Optimal Patient Positioning and Strategy for the Treatment of Proximal Ureteral Stones

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Ureteroscopic management of proximal ureteral stones presents technical challenges including stone retropulsion, prolonged operative time, and conversion to intrarenal treatment. Reverse Trendelenburg positioning has been shown to reduce proximal stone migration and operative time in ureteral stones, while the T-tilt position improves intrarenal stone clearance. The optimal strategy for proximal ureteral stones (treating stones in situ using reverse Trendelenburg versus pushing stones into the kidney followed by intrarenal treatment in T-tilt) remains unknown. This randomized controlled trial compares these two strategies, with primary focus on operative time as a measure of procedural efficiency. A total of 54 patients (27 per arm) will be enrolled at Mount Sinai West.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Adults aged 18 years and older.

• Diagnosed with kidney stones and scheduled for fURS.

• Stone burden \> 1 cm and/or multiple stones will be eligible.

• Able and willing to provide informed consent.

Locations
United States
New York
Mount Sinai West
RECRUITING
New York
Contact Information
Primary
Mantu Gupta, MD
mantu.gupta@mountsinai.org
212-241-1272
Backup
Blair Gallante, MPH
blair.gallante@mountsinai.org
212-241-1272
Time Frame
Start Date: 2026-05-21
Estimated Completion Date: 2027-12
Participants
Target number of participants: 54
Treatments
Experimental: Reverse Trendelenburg Position
Participants undergo ureteroscopic lithotripsy in reverse Trendelenburg positioning with attempted in situ treatment of the proximal ureteral stone to minimize proximal migration.
Active_comparator: T-Tilt Position
Participants undergo intentional relocation of the proximal ureteral stone into the kidney followed by intrarenal lithotripsy performed in the T-tilt position.
Related Therapeutic Areas
Sponsors
Leads: Icahn School of Medicine at Mount Sinai

This content was sourced from clinicaltrials.gov