Renal Biopsies in Post-liver Transplantation Patients With Renal Impairment: a Single-center, Prospective Cohort Study
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Behavioral
Study Type: Observational
SUMMARY
Investigators will conduct this single-center, prospective cohort study to explore the prevalence and risk factors of renal function progression in post-liver transplantation patients with renal impairment after renal biospy and to understand the the pathology of kidney disease in post-liver transplantation patients with renal impairment.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:
• age 18-75 years
• patients received liver transplantation
• new onset of proteinuria(defined as 24-hour proteinuria\>1g/24h, or Urinary albumin creatinine ratio(UACR)\>300mg/g at least two occasions
• have received renal biopsy in the past 3 months
• Signed informed consent form(ICF)
Locations
Other Locations
China
Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine
NOT_YET_RECRUITING
Shanghai
Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine
RECRUITING
Shanghai
Contact Information
Primary
Shan Mou, Dr
shan_mou@126.com
13918221242
Backup
Haijiao Jin, Dr
jinhaijiao1108@126.com
13917735313
Time Frame
Start Date: 2022-06-01
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 369
Treatments
renal biopsy
Standard percutaneous biopsy has been performed in all participants. Light microscope, fluorescence microscope and electron microscope were used for assessment of kidney issue
Related Therapeutic Areas
Sponsors
Leads: RenJi Hospital