A Prospective Randomized Multicentre Trial for Lymphadenectomy in Early-stage Ovarian Cancer

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

To assess the impact of comprehensive staging surgery with no lymphadenectomy on survival and quality of life in patients with early-stage ovarian cancer.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:

• Women aged 18 years to 70 years.

• Primary diagnosis of epithelial ovarian cancer FIGO stage IA-IIA ( recevive no prior treatment or receive incomplete initial surgery),with indications of adjuvant chemotherapy:①High-grade serous carcinoma; ②Grade 3 endometrioid carcinoma; ③Clear cell carcinoma; ④Grade 2 endometrioid carcinoma with capsule ruptured or pelvic tissues extension ⑤Low-grade serous carcinoma、Grade 1 endometrioid carcinoma and Mucinous carcinoma of the ovary with pelvic tissues extension.

• Patients who have given their signed and written informed consent.

• Good performance status (ECOG 0/1).

Locations
Other Locations
China
Department of Gynecologic Oncology, Sun Yat-sen University Cancer Center
RECRUITING
Guangzhou
Contact Information
Primary
Jihong Liu, Ph.D.
liujih@mail.sysu.edu.cn
86-20-87343102
Backup
Ting Deng, Ph.D.
dengting@sysucc.org.cn
86-20-87343105
Time Frame
Start Date: 2021-01-31
Estimated Completion Date: 2028-12-31
Participants
Target number of participants: 656
Treatments
Experimental: No Lymphadenectomy
Comprehensive staging surgery with no Lymphadenectomy
Active_comparator: Lymphadenectomy
Completion staging surgery including systematic pelvic and para-aortic lymphadenectomy
Sponsors
Leads: Sun Yat-sen University

This content was sourced from clinicaltrials.gov