A Randomized Clinical Trial of the LYMPHA Procedure for the Prevention of Lymphedema After Axillary Lymphadenectomy

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Lymphedema is a chronic, progressive, and debilitating condition that occurs with disruption or obstruction of the lymphatic system, which commonly occurs a result of breast cancer therapy. The purpose of this study is to determine if the use of a low risk lymphatic reconstruction procedure at the time of axillary lymph node dissection will reduce the risk of developing lymphedema. Additionally, to determine if this procedure improves objective outcomes of lymphedema and patient quality of life

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• Ages 18 to 75 years (inclusive)

• Patients undergoing unilateral or bilateral breast cancer related axillary lymphadenectomy

• Free of distant metastasis in preoperative screening

• Histology results of axillary lymph nodes could be either Negative or Positive

• Patients who undergo preoperative chemotherapy can be included

• Willingness and ability to provide written informed consent

• Willingness and ability to comply with all study procedures

Locations
United States
California
Stanford Cancer Institute
RECRUITING
San Francisco
Contact Information
Primary
Dung Nguyen, MD, PharmD
nguyendh@stanford.edu
6504929239
Time Frame
Start Date: 2021-09-10
Estimated Completion Date: 2030-06-01
Participants
Target number of participants: 80
Treatments
Other: Group A
Group A will under axillary lymphadenectomy alone
Active_comparator: Group B
Group B will undergo axillary lymphadenectomy with soft tissue reinforcement(STR)
Experimental: Group C
Group B will undergo axillary lymphadenectomy with immediate lymphatic reconstruction (LYMPHA) using reverse mapping using the SPY System.
Sponsors
Leads: Stanford University

This content was sourced from clinicaltrials.gov