The Impact of Socioeconomic Determinants on the Patient Reported Outcomes in Young Breast Cancer Patients After Breast Surgery: an Observational Cohort Study

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Observational
SUMMARY

Breast-conserving surgery is the standard treatment for young breast cancer patients, while mastectomy with breast reconstruction is an alternative for those who are not eligible for Breast-conserving surgery. Several studies have compared the quality of life and patient satisfaction among individuals receiving different types of surgery (Breast-conserving surgery, mastectomy alone, or mastectomy with reconstruction). For example, Meghan R. demonstrated that patients undergoing Breast-conserving surgery experience a higher quality of life compared to those undergoing mastectomy with breast reconstruction, whereas J. Dauplat's study showed that patients who undergo mastectomy with breast reconstruction report a higher quality of life than those who undergo mastectomy alone. However, the investigators hypothesize that the advantages of a specific type of surgery over another, such as Breast-conserving surgery versus breast reconstruction, may vary among patients with different socioeconomic factors. For instance, the benefits of breast reconstruction over Breast-conserving surgery might be more pronounced in young patients who require a more socially active lifestyle. Additionally, the benefits of one type of surgery over another may also vary at different time points during post-operative follow-up. Furthermore, it is worth noting that most current studies have been conducted in Caucasian populations. In contrast to Caucasians, Asians typically have smaller breast volumes, potentially leading to more significant defects after Breast-conserving surgery and possibly poorer aesthetic outcomes. Therefore, a study focusing on Asian young breast cancer populations is necessary.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 50
View:

• Age between 18 and 50 years old.

• The surgery time and procedure have been confirmed, and the surgical informed consent and research informed consent forms have been signed.

• Informed consent obtained from patient.

• Unilateral Breast Cancer.

• Good health,the patient is able to tolerate general anesthesia and surgery, with an ECOG performance status of ≤2 points.

• No history of breast/axillary radiation therapy.

• Willing and capable of complying with the study protocol visits, treatment plans, and other research procedures.

Locations
Other Locations
China
Sun Yat-sen Memorial Hospital,Sun Yat-sen University
RECRUITING
Guangzhou
Contact Information
Primary
Kai Chen, MD
chenkai23@mail.sysu.edu.cn
15920164730
Time Frame
Start Date: 2024-02-29
Estimated Completion Date: 2035-12-01
Participants
Target number of participants: 1000
Treatments
Breast-conserving surgery
Mastectomy
Mastectomy with reconstruction
Related Therapeutic Areas
Sponsors
Leads: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

This content was sourced from clinicaltrials.gov