Evaluation of the Safety and Effectiveness of the GORE® Tissue Reinforcement for Breast Reconstruction Device (TRBR Device) When Used in the Reinforcement of Breast Reconstruction

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The GORE Tissue Reinforcement for Breast Reconstruction (TRBR) research study will look at breast reconstruction during mastectomy procedures. There will be two arms in this study, a Treatment Arm, where data will be collected for a new medical device called the Tissue Reinforcement for Breast Reconstruction (TRBR) Device and a Control Arm where data will be collected from subjects who have previously had surgery and received no additional tissue reinforcement in their breast reconstruction surgery. This research study will look at the safety of the Study Device and the success of the participants breast reconstruction. The Study Device is investigational, which means it has not yet been used nor approved by the FDA for this treatment. The data collected in this study will be compared to the data collected in the Control Arm.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 22
Healthy Volunteers: f
View:

• Female subjects ≥ 22 years of age.

• First-time breast reconstruction post-mastectomy for target breast(s).

• Scheduled to undergo unilateral or bilateral mastectomy with immediate, two-stage, implant-based, subpectoral or prepectoral breast reconstruction after mastectomy.

• Mastectomy performed to address breast cancer or for cancer prophylaxis.

• An informed consent form is signed by Subject or Legally Authorized Representative (LAR).

• Subject is capable of following protocol procedures and complying with follow-up visit requirements

Locations
United States
Mississippi
University of Mississippi
RECRUITING
Jackson
Pennsylvania
University of Pennsylvania
RECRUITING
Philadelphia
Contact Information
Primary
Jill Ellis-Herr
TBR22-07@wlgore.com
1 800-437-8181
Backup
Ariana O'Neill
TBR22-07@wlgore.com
1 800-437-8181
Time Frame
Start Date: 2025-04-09
Estimated Completion Date: 2029-09
Participants
Target number of participants: 180
Treatments
Experimental: Prospective Arm
Prospectively treated subjects who undergo two-stage implant-based breast reconstruction with the TRBR Device (TRBR Device group)
Related Therapeutic Areas
Sponsors
Leads: W.L.Gore & Associates
Collaborators: Avania

This content was sourced from clinicaltrials.gov