Dexmedetomidine Ropivacaine Versus Plain Ropivacaine in Bilateral Pectoralis Nerve (PECS) Block for Fast Tracking and Postoperative Analgesia in Open Heart Surgery Through Midline Sternotomy. A Randomized Clinical Trial

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

In 2012 Blanco et al. \[1\] described the ultrasound technique for Pectoral nerve (PECS) block as a new, less invasive regional analgesic technique for breast surgeries. PECS block includes PECS I and PECS II (modified PECS I) interfascial blocks. Since that time, PECS block has been used successfully with good results for a wide variety of surgeries on the chest wall such as radical mastectomies, breast-conserving surgeries, breast implant placement, automated implantable cardioverter-defibrillator (AICD)/pacemaker placement, intercostal drainage tube placement, and rib fractures. In this study, the investigators hypothesized that adding dexmedetomidine as an adjuvant to ropivacaine can result in the prolongation of the duration of anesthesia with improvement of the quality of postoperative analgesia of bilateral PECS block for patients undergoing cardiac surgery via midline sternotomy compared with using only plain ropivacaine.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Maximum Age: 65
Healthy Volunteers: t
View:

• Age 20 - 65 years,

• Ejection fraction (EF) \> 35%,

• Elective isolated CABG, or Valve surgery

Locations
Other Locations
Egypt
Fayoum University Hospital
COMPLETED
Al Fayyum
Mohamed Hamed
RECRUITING
Al Fayyum
Contact Information
Primary
mina fam, M.D
mms12@fayoum.edu.eg
01025273637
Backup
Mostafa Elhamamsy, M.D
mostafah333@gmail.com
+966 56 879 9134
Time Frame
Start Date: 2024-10-10
Estimated Completion Date: 2025-01-08
Participants
Target number of participants: 90
Treatments
Active_comparator: Group (DR)
will receive 30 ml of 0.25% ropivacaine + dexmedetomidine 0.5 μg/kg for each side.
Active_comparator: Group (R)
will receive 30 ml of 0.25% of plain ropivacaine for each side.
Sham_comparator: Group (C)
the control group will not receive any regional anesthesia and only will receive fentanyl 1μg/kg/hr.
Related Therapeutic Areas
Sponsors
Leads: Fayoum University

This content was sourced from clinicaltrials.gov