Impact of Tranexamic Acid Use on Blood Loss and Transfusion Rates After Hip Reconstruction in Children, A Randomized Controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Procedure, Other, Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Surgical hip reconstruction reduces the hip joint through soft tissue releases and osteotomies of the femur and/or pelvis. Blood loss and subsequent blood transfusion are normal consequences of hip reconstruction.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 1
Maximum Age: 18
Healthy Volunteers: f
View:
• ASA I - II
• Scheduled for acetabular osteotomy and/or proximal femoral derotation osteotomies.
Locations
Other Locations
Egypt
Assiut University
RECRUITING
Asyut
Contact Information
Primary
Shimaa A Hassan, M.D.
shimaa.abbas@med.aun.edu.eg
01002953253
Backup
Amira A Abdel-rahman, M.B.B.CH
amiraali441994@gmail.com
01002595850
Time Frame
Start Date: 2025-04-03
Estimated Completion Date: 2025-12
Participants
Target number of participants: 400
Treatments
Active_comparator: T group
each participant will receive 15 mg/kg of tranexamic acid diluted in a 10 mL syringe slowly over 10-15 minutes, 15 minutes before skin incision.
Active_comparator: TC group
each participant will receive 10 mg/kg of tranexamic acid diluted in a 5 mL syringe slowly over 5 minutes, 15 minutes before skin incision, and A caudal epidural block with 1 mL/kg of 0.25% bupivacaine.
Active_comparator: C group
each participant will receive a caudal epidural block with 1 mL/kg of 0.25% bupivacaine.
Placebo_comparator: P group
participants will receive the regular standard care without adding tranexamic acid or caudal epidural block
Related Therapeutic Areas
Sponsors
Leads: Assiut University