Recurrence of T1D in Pancreas Transplantation
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The hypothesis is that humoral and cellular islet-specific responses are an early risk factor for recurrence of autoimmunity and hyperglycemia in simultaneous pancreas-kidney (SPK) recipients independent of alloimmunity. This study will test the hypothesis and will assess their individual and combined predictive value.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: No
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• Patient has been fully informed and has signed a dated IRB approval informed consent form and is willing to follow study procedures for the extent of the study (24 months). Parent or legal guardian must provide written consent for patients <18 years of age.
• Age 18-75 years.
• Recipient of simultaneous pancreas and kidney transplant
• Primary or secondary renal allograft: living or deceased
Locations
United States
Florida
University of Miami Miller School of Medicine Transplant Clinic
Recruiting
Miami
Contact Information
Primary
George Burke, M.D.
gburke@med.miami.edu
305-355-5111
Backup
Lissett Moni
ltueros@med.miami.edu
3052435325
Time Frame
Start Date: May 2005
Estimated Completion Date: May 2023
Participants
Target number of participants: 400
Treatments
pancreas-kidney transplant
pancreas-kidney transplant recipients with type 1 diabetes.
Authors
George Burke
Related Therapeutic Areas
Sponsors
Leads: University of Miami