Thrombus Aspiration in Primary Percutaneous Coronary Intervention for STEMI Patients With High Thrombus Burden
Status: Recruiting
Location: See all (50) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This is a prospective, multicenter, open-label, randomized, controlled, parallel group study, in which ST-segment Elevation Myocardial Infarction (STEMI) patients with high thrombus burden(TIMI thrombus grade ≥3) are included. Patients are randomized to be treated with or without manual thrombus aspiration(TA) during primary percutaneous coronary intervention(PPCI) by a ratio of 1:1.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age ≥ 18 years;
• STEMI patients undergoing primary PCI within 12 hours after the onset of symptoms;
• High thrombus burden after guidewire passes the lesion (TIMI thrombus grade ≥3);
• Informed consent must be voluntary;
Locations
Other Locations
China
The Second Xiangya Hospital of Central South University
NOT_YET_RECRUITING
Changsha
The Third Xiangya Hospital of Central South University
NOT_YET_RECRUITING
Changsha
Sichuan Provincial People's Hospital
NOT_YET_RECRUITING
Chengdu
West China Hospital
NOT_YET_RECRUITING
Chengdu
First People's Hospital of Foshan
NOT_YET_RECRUITING
Foshan
First People's Hospital of Shunde (Affiliated Hospital at Shunde, Southern Medical University)
NOT_YET_RECRUITING
Foshan
The Second People's Hospital of Nanhai District
RECRUITING
Foshan
Fujian Provincial Hospital
NOT_YET_RECRUITING
Fuzhou
GanZhou Municopal Hospital
NOT_YET_RECRUITING
Ganzhou
Shangyou Hospital
NOT_YET_RECRUITING
Ganzhou
Guangdong Provincial Hospital of traditional Chinese Medicine
NOT_YET_RECRUITING
Guangzhou
Guangdong Provincial People's Hospital
NOT_YET_RECRUITING
Guangzhou
Guangzhou General Hospital of Guangzhou Military Command
NOT_YET_RECRUITING
Guangzhou
Guangzhou Panyu Central Hospital
NOT_YET_RECRUITING
Guangzhou
Huadu District People's Hospital of Guangzhou
NOT_YET_RECRUITING
Guangzhou
Huangpu Division of The First Affiliated Hospital, Sun Yat-sen University
NOT_YET_RECRUITING
Guangzhou
Nanfang Hospital
NOT_YET_RECRUITING
Guangzhou
The First Affiliated Hospital of Guangzhou Medical University
NOT_YET_RECRUITING
Guangzhou
The first Affiliated Hospital, Sun Yat-Sen University
NOT_YET_RECRUITING
Guangzhou
The Second Affiliated Hospital, Sun Yat-Sen University
NOT_YET_RECRUITING
Guangzhou
Zhujiang Hospital of Southern Medical University
NOT_YET_RECRUITING
Guangzhou
Guilin people's Hospital
NOT_YET_RECRUITING
Guilin
Hainan People's Hospital
NOT_YET_RECRUITING
Haikou
The Second Clinical College of Hainan Medical University
NOT_YET_RECRUITING
Haikou
Huizhou Third People's Hospital
NOT_YET_RECRUITING
Huizhou
Jiangmen Central Hospital
NOT_YET_RECRUITING
Jiangmen
Kaiping Central Hospital
RECRUITING
Kaiping
Kashgar first people's Hospital
NOT_YET_RECRUITING
Kashgar
Yan'an Hospital of Kunming City
NOT_YET_RECRUITING
Kunming
Maoming People's Hospital
NOT_YET_RECRUITING
Maoming
The Second Affiliated Hospital of Shantou university Medical College
RECRUITING
Shantou
Yue Bei People's Hospital
NOT_YET_RECRUITING
Shaoguan
Shaoxing people's Hospital
NOT_YET_RECRUITING
Shaoxing
Peking University Shenzhen Hospital
NOT_YET_RECRUITING
Shenzhen
Shenzhen Bao'an District People's Hospital
NOT_YET_RECRUITING
Shenzhen
Shenzhen People's Hospital
NOT_YET_RECRUITING
Shenzhen
The Eighth Affiliated Hospital, Sun Yat-Sen University
NOT_YET_RECRUITING
Shenzhen
Taishan people's Hospital
NOT_YET_RECRUITING
Taishan
The First Affilicated Hospital of Xinjiang Medical University
NOT_YET_RECRUITING
Ürümqi
Affiliated Hospital, Weifang Medical University
NOT_YET_RECRUITING
Weifang
The First Affiliated Hospital of Wenzhou Medical University
NOT_YET_RECRUITING
Wenzhou
Wuhan Asia Heart Hospital
NOT_YET_RECRUITING
Wuhan
The first Affiliated Hospital of Xi'an Jiaotong University
NOT_YET_RECRUITING
Xi’an
Nanxiong people's Hospital
NOT_YET_RECRUITING
Xiongzhou
People's Hospital of Yangjiang City
RECRUITING
Yangjiang
The Second Affiliated Hospital of Guangdong Medical University
NOT_YET_RECRUITING
Zhanjiang
Sihui people's Hospital
RECRUITING
Zhaoqing
Zhongshan People's Hospital
NOT_YET_RECRUITING
Zhongshan
The Fifth Affiliated Hospital, Sun Yat-Sen University
NOT_YET_RECRUITING
Zhuhai
Zhuhai people's Hospital
NOT_YET_RECRUITING
Zhuhai
Contact Information
Primary
Pengchen He, MD
drhepengcheng@aliyun.co
86-13829730152
Time Frame
Start Date: 2020-08-30
Estimated Completion Date: 2026-02-28
Participants
Target number of participants: 3838
Treatments
Experimental: Thrombus aspiration
Upfront manual thrombus aspiration followed by PCI
Active_comparator: PCI Alone
PCI without upfront manual thrombus aspiration
Related Therapeutic Areas
Sponsors
Leads: Guangdong Provincial People's Hospital
Collaborators: Yuebei People's Hospital, Jiangmen Central Hospital, Meizhou Traditional Chinese Medicine Hospital, Nanning Second People's Hospital, Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen Third People's Hospital, Shenzhen Longhua District Central Hospital, People's Hospital of Yingde City, Sihui City People's Hospital, Heyuan people's Hospital, Guangxi Zhuang Autonomous Region Nationalities Hospital, People's Hospital of Nanhai District, Foshan, Guangzhou Hospital of integrated Traditional and West Medicine, Dongguan People's Hospital, Luhe County People's Hospital, Taishan People's Hospital, Weifang Medical University, Shantou Central Hospital, Guangning People's Hospital, Kaiping Central Hospital, The First People's Hospital of Kashgar Erea, The Third Affiliated Hospital of Guangzhou Medical University, The Fourth People's Hospital of Chenzhou, People's Hospital of Dapu County, Second Affiliated Hospital of Shantou University Medical College, Shenzhen Baoan People's Hospital, The Second People's Hospital of Foshan, Longgang District People's Hospital of Shenzhen, People's Hospital of Xinjiang Uygur Autonomous Region, Shenzhen People's Hospital, The Third Affiliated Hospital of Sun Yat-Sen University, Yuedong Hospital, Tongxiang First People's Hospital, Qingyuan People's Hospital, Wuzhou Gongren Hospital, The Second Affiliated Hospital of Dalian Medical University, Huaiji People's Hospital, Yangchun People's Hospital, Liuzhou Municipal Liutie Central Hospital, Zhongshan Hospital Of Traditional Chinese Medicine, Bobai County People's Hospital, Guangxi, Chen Zhou 3RD People's Hospital, Zhaoqing Gaoyao People's Hospital, The Second People's Hospital of Nanhai District of Foshan, People's Hospital of Nanxiong County, Yangjiang People's Hospital, Shenzhen Baoan District Shiyan People's Hospital, The Third Xiangya Hospital of Central South University, First People's Hospital of Foshan, Lianzhou People's Hospital, Shangyou People's Hospital, Qingyuan Hospital of Traditional Chinese Medicine Affiliated To Guangzhou University of Traditional Chinese Medicine, Dafeng Hospital of Chaoyang District in Shantou City, Lianping Xian Ren Ming Yi Yuan, Foshan Sanshui District People's Hospital, Zhongshan People's Hospital, Guangdong, China, The Affiliated Shunde Hospital of Jinan University