Impact of Rotational Atherectomy on Coronary Microvascular Function in Patients With Stable Angina and Calcified Coronary Artery Disease

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this observational study is to compare the impact of rotational atherectomy to conventional stenting and to investigate how it may affect coronary microcirculation in patients with calcified coronary artery lesions and stable CAD. The study's objectives are to: * investigate the impact of rotational atherectomy on the prevalence of post-percutaneuos coronary intervention coronay microvascular dysfunction; * investigate the impact of conventional stenting on the prevalence of post-percutaneuos coronary intervention coronay microvascular dysfunction; and * compare the impact of both percutaneuos coronary interventions on coronary microvascular dysfunction. Patients with calcified lesions will be enrolled prospectively and will have serial invasive and non-invasive microvascular testing prior to and after rotational atherectomy or conventional stenting.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Healthy Volunteers: f
View:

• Patient diagnosed with stable coronary artery calcified lesion requiring Percutaneous coronary intervention

Locations
Other Locations
Lithuania
Lithuanian University of Health Sciences
RECRUITING
Kaunas
Contact Information
Primary
Ali Aldujeli
ali.aldujeli@kaunoklinikos.lt
+37064874874
Time Frame
Start Date: 2023-05-01
Estimated Completion Date: 2025-05-01
Participants
Target number of participants: 300
Treatments
Active_comparator: Rotational Atherectomy
Patients who are scheduled to have rotational atherectomy will be labeled in this group; patients in this group will have invasive and non-invasive microvascular testing before and after the rotational atherectomy procedure.
Active_comparator: Conventional Stenting
Patients who are scheduled to have conventional stenting will be labeled in this group; patients in this group will have invasive and non-invasive microvascular testing before and after the conventional stenting procedure.
Sponsors
Collaborators: Kreiskrankenhaus Rotenburg an der fluda, Alkafeel Super Speciality Hospital, Klaipėda University
Leads: Lithuanian University of Health Sciences

This content was sourced from clinicaltrials.gov