Reduced Stent Strategy Versus Conventional Percutaneous Coronary Revascularization in Patients Presenting With St-segment Elevation Myocardial Infarction (Copernican)
Status: Recruiting
Location: See all (23) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The objective is to compare a reduced stent strategy based on drug-coated balloon (DCB) percutaneous coronary intervention (PCI) with conventional drug-eluting stent (DES) coronary revascularization in patients presenting with ST-segment myocardial infarction (STEMI). Randomization will be performed after successful culprit-lesion guidewire crossing and flow restoration. Random allocation in a 1:1 fashion to one of the following strategies: * Study group: reduced stent PCI strategy (DCB-based) * Control group: conventional PCI strategy (DES-based).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• \- Patients presenting with STEMI and indication to undergo pPCI.
Locations
Other Locations
Spain
Complejo Hospitalario Universitario de A Coruña
RECRUITING
A Coruña
Hospital Universitario de Burgos
RECRUITING
Burgos
Consorcio Hospitalario Provincial de Castellon
RECRUITING
Castelló
Hospital Universitario Reina Sofía de Córdoba
RECRUITING
Córdoba
Hospital General Universitario de Elche
RECRUITING
Elche
Hospital Universitario Clínico San Cecilio
RECRUITING
Granada
Hospital Universitario Juan Ramón Jiménez
RECRUITING
Huelva
Hospital Universitari de Bellvitge
RECRUITING
L'hospitalet De Llobregat
Hospital Universitario de La Princesa
RECRUITING
Madrid
Hospital Universitario La Paz
RECRUITING
Madrid
Hospital Universitario Puerta de Hierro Majadahonda
RECRUITING
Madrid
Hospital Universitario Regional de Malaga
RECRUITING
Málaga
Hospital de Mérida
RECRUITING
Mérida
Hospital Universitario de Navarra
RECRUITING
Pamplona
Complejo Hospitalario Universitario de Santiago de Compostela
RECRUITING
Santiago De Compostela
Hospital Universitario Virgen Del Rocio
RECRUITING
Seville
Hospital Universitari Joan Xxiii de Tarragona
RECRUITING
Tarragona
Hospital Universitario Mutua de Terrassa
RECRUITING
Terrassa
Consorcio Hospital General Universitario de Valencia
RECRUITING
Valencia
Hospital Universitario Y Politecnico La Fe
RECRUITING
Valencia
Hospital Clinico Universitario de Valladolid
RECRUITING
Valladolid
Hospital Clinico Universitario Lozano Blesa
RECRUITING
Zaragoza
Hospital Universitario Miguel Servet
RECRUITING
Zaragoza
Contact Information
Primary
Naiara García Lamas
naiara@pinvestiga.com
634213101
Backup
Marta Fernández Álvarez
marta@pinvestiga.com
604037828
Time Frame
Start Date: 2024-03-11
Estimated Completion Date: 2035-09
Participants
Target number of participants: 1272
Treatments
Experimental: DCB-based
Reduced stent PCI strategy: Culprit lesion revascularization with DCB will be performed after coronary predilation if residual stenosis ≤30%, lack of dissections \>type B and TIMI 3 flow. If the aforementioned culprit-lesion characteristics are not achieved after DCB-PCI, a DES will be implanted.
No_intervention: DES-based
Control group
Related Therapeutic Areas
Sponsors
Collaborators: ERA4Health
Leads: Hospital Universitario La Fe