Characteristics of Calcification in a Chronic Total Occlusion on Computed Tomography Coronary Angiogram and Percutaneous Coronary Intervention Outcomes- a Single Centre Observational Study

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

A chronic total occlusion (CTO) is present in 15-20% of patients who are referred for invasive coronary angiography. CTO Percutaneous Coronary Intervention (PCI) procedure success rates have increased over the years and can be as high as 90% when performed by high-volume CTO operators.Procedurally, excess calcification in the CTO anatomy is one factor which makes it difficult to complete the procedure or obtain ideal stent expansion. Excess calcification is best identified by Computed Tomography Coronary Angiography (CTCA) rather than invasive angiography. The investigators plan to retrospectively evaluate CTCA in patients who underwent CTO PCI and correlate calcification characteristics with CTO PCI outcomes and tools utilised for calcium modification.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients meeting all the below criteria will be included

‣ ≥18 years

⁃ Previous CTO PCI attempt in the last 5 years

⁃ Undergone CTCA either pre or post CTO PCI

⁃ Adequate CTCA images for analysis

Locations
Other Locations
United Kingdom
Birmingham City Hospital, Sandwell and West Birmingham NHS Trust
RECRUITING
Birmingham
Contact Information
Primary
Vinoda Sharma, FRCP
vinodasharma@nhs.net
+44(0)1215075841
Backup
Kelly Hard
swbh.randd.generic@nhs.net
+44(0)121 507 4811
Time Frame
Start Date: 2024-07-19
Estimated Completion Date: 2025-07-01
Participants
Target number of participants: 100
Treatments
CTO patients who underwent attempted PCI
Patients with coronary CTO who underwent attempt at PCI and also underwent a CTCA
Sponsors
Leads: Sandwell & West Birmingham Hospitals NHS Trust

This content was sourced from clinicaltrials.gov