Timing of Anticoagulant Administration During Radial Access Percutaneous Coronary Intervention: the HERA-PCI Study (Heparin Early for Radial Access Percutaneous Coronary Intervention)

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

While the reduced hemorrhagic risk of radial access for percutaneous coronary intervention compared to femoral access is well-established, its main complication remains radial artery occlusion, which can occur in up to 30% of patients. Anticoagulation is the primary preventive measure recommended in clinical practice to reduce the risk of this complication, typically involving heparin injection during the procedure in most centers. However, data on the effect of the timing of heparin injection are limited. The investigators hypothesize that injection of heparin before sheath insertion may reduce the rate of radial artery occlusion compared with injection after sheath insertion.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients having 18 years old or older, regardless of gender, undergoing percutaneous radial coronary intervention

• Subject affiliated to a social protection health insurance

• Subject able to understand the objectives and risks of the research and to provide dated and signed consent

• Subject who has been informed of the results of the preliminary medical examination

Locations
Other Locations
France
Hôpitaux Universitaires de Strasbourg
RECRUITING
Strasbourg
Contact Information
Primary
Pr Patrick OHLMANN Pr Patrick OHLMANN, Professor
patrick.ohlmann@chru-strasbourg.fr
03.69.55.09.53
Time Frame
Start Date: 2025-06-05
Estimated Completion Date: 2026-01
Participants
Target number of participants: 550
Treatments
Active_comparator: heparin delayed injection
Administration of heparin after sheath insertion
Experimental: heparin early injection
Administration of heparin prior to sheath insertion
Sponsors
Leads: University Hospital, Strasbourg, France

This content was sourced from clinicaltrials.gov