Optimizing Pain Control in Transurethral Resection of the Prostate
Who is this study for? Patients undergoing transurethral resection of the prostate
What treatments are being studied? Ibuprofen+Education
Status: Recruiting
Location: See location...
Intervention Type: Behavioral, Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
The purpose of this study is to develop a multi-modal protocol for pain management after TURP that minimizes opioid use. The investigators hypothesize this approach will provide non-inferior pain control to the current standard of care which includes opioids as the primary agent. The investigators believe this is an important step in reducing the opioid epidemic in surgical patients.
Eligibility
Participation Requirements
Sex: Male
Minimum Age: 18
Healthy Volunteers: t
View:
• Are identified as candidates for TURP
• Are 18 years of age or greater
• Are proficient in English
Locations
United States
Washington
Virginia Mason Medical Center
RECRUITING
Seattle
Contact Information
Primary
Ryan Donahue, MD
ryan.donahue@vmmc.org
2062236600
Time Frame
Start Date: 2017-12-08
Estimated Completion Date: 2019-12-01
Participants
Target number of participants: 50
Treatments
No_intervention: Standard of care arm
The standard of care group will group will receive the following regimen while inpatient:~* 2% topical lidocaine gel applied to catheter tip as needed for pain, maximum dose of 600mg in 12 hours~* Acetaminophen 1000mg every 8 hours standing~* Oxycodone 5mg PO every 4 hours as needed pain~* Phenazopyridine 100mg TID as needed for urinary burning~* Senna 1 tab every 12 hours~* Miralax 17g powder once daily as needed for constipation~The standard of care group will get the following prescriptions on discharge:~* Oxycodone 5mg every 4 hours as needed pain - 15 tabs~* Acetaminophen 1000mg every 8 hours standing for two days then as needed~* Phenazopyridine 100mg TID as needed for urinary burning - 9 tabs~* Senna 1 tab every 12 hours - 10 tabs
Experimental: Multi-modal group
The multi-modal group will receive the following regimen while inpatient:~* 2% topical lidocaine gel applied to catheter tip as needed for pain, maximum dose of 600mg in 12 hours~* Acetaminophen 1000mg every 8 hours standing~* Ibuprofen 600mg every 6 hours standing~* Oxycodone 5mg PO every 4 hours as needed pain~* Phenazopyridine 100mg TID as needed for urinary burning~* Senna 1 tab every 12 hours~* Miralax 17g powder once daily as needed for constipation~* Patient Education (Figures 2 \& 3)~The multi-modal group will receive the following prescriptions on discharge:~* Acetaminophen 1000mg every 8 hours standing for two days then as needed - 30 tabs~* Ibuprofen 600mg every 8 hours standing for two days then as needed - 30 tabs~* Phenazopyridine 100mg TID as needed for urinary burning - 9 tabs~* Senna 1 tab every 12 hours - 10 tabs
Related Therapeutic Areas
Sponsors
Collaborators: Virginia Mason Hospital/Medical Center
Leads: Benaroya Research Institute