Intraoperative Bedside Lung-ultrasound Use to Optimize Positive End-expiratory Pressure for Elective Robotic-assisted Radical Prostatectomy or Cystectomy Patients: a Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

There is an increasing trend in the use of robotic-assisted radical prostatectomy or cystectomy (RARPC). Preventing lung atelectasis without inducing overdistention of the lung is challenging. Many studies tried to optimize PEEP titration by using methods such as dead space fraction guided and static pulmonary compliance directed techniques, or by using electrical impedance tomography. However, the use of these methods is limited by inaccuracy and the need for sophisticated devices. Bedside Lung ultrasound is fast, easy and economic technique that is gaining interest in the operating room. Ultrasound-guided PEEP titration has been used in bariatric surgeries (different position and usually shorter procedure time) and proved effective in improving oxygenation, compliance and reducing the incidence of postoperative pulmonary atelectasis and hypoxia without causing hemodynamic instability. The aim of this study is to evaluate the effectiveness of intraoperative individualized lung ultrasound-guided stepwise PEEP optimization in patients undergoing RARPC on oxygenation, intraoperative and early postoperative pulmonary complications.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:

• ASA I, II \& III.

• Normal respiratory functions or mild lung disease.

Locations
Other Locations
Egypt
Cairo University Hospitals
RECRUITING
Cairo
Contact Information
Primary
Mustafa E Mohamed, MD
mustafaemam931@gmail.com
01140806330
Backup
Nazmy S Mikhael, MD
nazmy.edwar.seif@gmail.com
01227400808
Time Frame
Start Date: 2024-04-01
Estimated Completion Date: 2025-06
Participants
Target number of participants: 88
Treatments
Experimental: US - PEEP group
Lung Ultrasound - guided Positive End Expiratory Pressure group
Active_comparator: Standard group
Standard Ventilation group
Sponsors
Leads: Nazmy Edward Seif

This content was sourced from clinicaltrials.gov